dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0002991
Uniprot Accession O77410; EIF3E_DROME; Q9VVA2;
Genbank Protein ID NP_477385.1;
Genbank Nucleotide ID NM_058037.5;
Protein Name Eukaryotic translation initiation factor 3 subunit E
Protein Synonyms/Alias
Gene Name eIF3-S6
Gene Synonyms/Alias Int6;CG9677;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)		 Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.
Phosphorylation Sites
 dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
104DILKNGESMKDSKTFcurated22817900
393VMGTQPLSPYQQLVEPHOSIDA;PhosphoPep 2.0;curated21081558; 19060867; 22817900
Sequence
(Fasta)		MANFDLTRIN CQFLDRHLTF PLLEFLCGKE IYNQQELLEY ILETVNKTNM IDYTMDTRKR 60
LNLSQEMPEE LVQRKAEVLA TLKQLQNEVA PIMKATDILK NGESMKDSKT FVNALQKDYN 120
FKVEHLESAY KLAKYLYECG NYQESTSYLY FCLIVMSPND KNYLNVLWGK LAAEILTLNW 180
NTALEDLTRL RDYIDNANFS TIQALQQRTW LIHWSVLVFF NHPKGRDLII EMFLYKPLYL 240
NAIQTMCPHI MRYLATAVVI NRTRRNALKD LIKVIQQESY TYRDPITEFL ECLYVNFDFE 300
GARLKLHECQ TVILNDFFIV ACLNEFVEDA RLMIFETFCR IHQCITISML ADKLNMKPNE 360
AECWIVNLIR NARLNAKIDS KLGHVVMGTQ PLSPYQQLVE KIDSLSMRSE HLAGLIERKS 420
KQKQNQESAD SWKYY 436
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
Interpro

IPR016650--eIF3e
IPR019010--eIF3e_N
IPR000717--PCI_dom
IPR011991--WHTH_DNA-bd_dom
PROSITE
Pfam

PF09440--eIF3_N
PF01399--PCI
Gene Ontology

GO:0016282--C:eukaryotic 43S preinitiation complex
GO:0033290--C:eukaryotic 48S preinitiation complex
GO:0005852--C:eukaryotic translation initiation factor 3 complex
GO:0043231--C:intracellular membrane-bounded organelle
GO:0005634--C:nucleus
GO:0003743--F:translation initiation factor activity
GO:0001731--P:formation of translation preinitiation complex
GO:0048812--P:neuron projection morphogenesis
GO:0006909--P:phagocytosis
GO:0051726--P:regulation of cell cycle
GO:0006446--P:regulation of translational initiation
GO:0006413--P:translational initiation