dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0002988
Uniprot Accession O77237; PELI_DROME;
Genbank Protein ID NP_001097890.1; NP_524466.1;
Genbank Nucleotide ID NM_001104420.3; NM_079742.4;
Protein Name Protein pellino
Protein Synonyms/Alias
Gene Name Pli
Gene Synonyms/Alias CG5212;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)		 Scaffold protein involved in the Toll signaling pathway via its interaction with pelle/pll kinase.
Phosphorylation Sites
 dbPAF PTMs: 5
PositionPeptidesSourceReferences ( PMIDs )
10KRTDGTESPILAEDGdbPTM 3.0;Phospho.ELM 9.0;PHOSIDA;UniProt;curated18327897; 16381945; 23193290; 21081558; 22817900
73SKHYIVQSPQTSKAIPhosphoPep 2.019060867
76YIVQSPQTSKAILDAPhosphoPep 2.019060867
91NQHSISYTLSRNQAVPhosphoPep 2.019060867
297QCPVGLNTLVIPRKVPhosphoPep 2.0;curated19060867; 22817900
Sequence
(Fasta)		MVKRTDGTES PILAEDGGDG HDKPRLRYGE LVILGYNGYL PQGDRGRRRS KFVLHKRTEA 60
SGVKRSKHYI VQSPQTSKAI LDANQHSISY TLSRNQAVIV EYKEDTETDM FQVGRSSESP 120
IDFVVMDTLP GDKKDAKVMQ STISRFACRI LVNRCEPAKA RIFAAGFDSS RNIFLGEKAT 180
KWQDNVEIDG LTTNGVLIMH PKGSFCGGNA KCGLWRECSV GGDVFSLRES RSAQQKGQPI 240
YDECNILQDG TLIDLCGATL LWRSAEGLQH SPTKHDLEKL IDAINAGRPQ CPVGLNTLVI 300
PRKVNIGDQV NQPYVYLNCG HVQGHHDWGQ DENTGARRCP MCLELGPVVT LCMGLEPAFY 360
VDVGAPTYAF NPCGHMATEK TVKYWANVEI PHGTNGFQAV CPFCATPLDG ATGYIKLIFQ 420
DNLD 425
Keyword

KW-0181--Complete proteome
KW-0597--Phosphoprotein
KW-1185--Reference proteome
Interpro

IPR006800--Pellino_fam
PROSITE
Pfam

PF04710--Pellino
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005886--C:plasma membrane
GO:0019207--F:kinase regulator activity
GO:0006955--P:immune response
GO:0008348--P:negative regulation of antimicrobial humoral response
GO:0045751--P:negative regulation of Toll signaling pathway
GO:1902524--P:positive regulation of protein K48-linked ubiquitination
GO:0042325--P:regulation of phosphorylation
GO:0008063--P:Toll signaling pathway