dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0002982
Uniprot Accession O76906; CRM_DROME; Q0KHW5; Q8MM10; Q8MM41; Q8MM71; Q8MX89; Q8MX90; Q8MX91; Q8MX92; Q8MX93; Q8MX94; Q8MX95; Q9W4V7;
Genbank Protein ID NP_477105.2; NP_726829.1;
Genbank Nucleotide ID NM_057757.4; NM_166951.2;
Protein Name Protein cramped
Protein Synonyms/Alias
Gene Name crm
Gene Synonyms/Alias CG2714;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)
Polycomb group (Pc-G) genes are needed to maintain expression patterns of the homeotic selector genes of the Antennapedia (Antp-C) and Bithorax (Bx-C) complexes, and hence for the maintenance of segmental determination. Can act as a modifier of position effect variegation (PEV).
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
431KKPKSSASPPLEKSLdbPTM 3.0;Phospho.ELM 9.0;PHOSIDA;SysPTM 2.0;UniProt18327897; 16381945; 23193290; 21081558; 19366988
437ASPPLEKSLDDGPLEdbPTM 3.0;Phospho.ELM 9.0;SysPTM 2.0;UniProt18327897; 16381945; 23193290; 19366988
Sequence
(Fasta)
MEELSKQPPP PPLTQPPPPS SSVSIEEPLP NGKGGGAVVV NSIAKLPEEE LLGSVTMHNC 60
PGTRASARVI QKMKQDQTRP MTPPPSEREP NKKEEKAAQK TPSQLKTGSG KTTWTNVERN 120
CFFDALNEFG KDFEAVANCI NAKLKRRNAN SDYSFKTKDQ VRQHYYQTHH KICKYVRFSE 180
ELKKPAQELY TLINYGEMRR KLQFLTEKHF MKLKQLVYQG QITVRCKGKN IRIKTPSCKA 240
LRRLNQLDDS LEDIRLPSKV EVLVTPANME AFGRVQSLAQ NPRGRIIVPL HKKLISFIKT 300
FEYKWRSANQ RLHEEKSAYF SSSLPSAASN NNNNNNETEP LQPSVASLDP SMCFQPRPGV 360
AIHRPLLSIT AYLSSISICL TAYEERMGFK VRSETLGNLA GMSVAANKRL RTESGSEKRS 420
PETKKPKSSA SPPLEKSLDD GPLEGNLMKM ENSSGDELGE EIHEFLGDIL EAMQHPQAAT 480
IPALSATTGD TTNVAVALET SHDPVQQAYP ANADLSNAMA TSVLQTSCAA APAPSTPVTG 540
SLAAPSVARS KRKEAKEAAA AAQARNFKPL LSDDILKRIR KGWTQANAAD ITIGDLYVVF 600
GQDSKLELEY YWCEVDSSTA MASSILTINT VTPSSSSVGT QTGSAASNAN QTGASSNCYV 660
SASSNSSTSS TSLPYNPNDC DSVERVRAVT TSSVSNKLKH LLLVANLSER VRKRQCNCGH 720
TCDRKRDLMT KAQQLAEATA TGGVGGMVEG NFRTPMLPVR RPISNIDPVR QLSALTRQKI 780
SRQVLVQRRL LPPTSAGDRP YDLLSVRQLH SGLFEPIDRV DGTSSAGIST SGSKPDCSMN 840
AMTASQDQEP GDQGALEFLN DEATQVSARD MPNLDICVAT NRTDVSSSLN EAAQDGSTTQ 900
SFFQGSMSPM HLLRDSTSNA RWLEDNINDF SLTSLLGHLD EIDATRDILD PSSSMSVISE 960
SSVDFRHKFQ EIAALLQQQE KD 983
Keyword

KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0238--DNA-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation

Interpro

IPR001005--SANT/Myb

PROSITE
Pfam
Gene Ontology

GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0003677--F:DNA binding
GO:0006355--P:regulation of transcription, DNA-templated
GO:0007379--P:segment specification
GO:0006351--P:transcription, DNA-templated