dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0002977
Uniprot Accession O76863; O76863_DROME;
Genbank Protein ID NP_570020.1;
Genbank Nucleotide ID NM_130664.4;
Protein Name EG:100G10.3 protein
Protein Synonyms/Alias
Gene Name eIF2B-beta
Gene Synonyms/Alias EG:100G10.3;CG2677;Dmel_CG2677;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 7
PositionPeptidesSourceReferences ( PMIDs )
100VQHFADDSQASLSLHPhosphoPep 2.0;curated19060867; 22817900
103FADDSQASLSLHKLVPhosphoPep 2.019060867
111LSLHKLVTQTSESNVPhosphoPep 2.019060867
113LHKLVTQTSESNVSVPhosphoPep 2.019060867
114HKLVTQTSESNVSVDPHOSIDA;PhosphoPep 2.0;curated21081558; 19060867; 22817900
116LVTQTSESNVSVDYSPHOSIDA;PhosphoPep 2.0;curated21081558; 19060867; 22817900
119QTSESNVSVDYSVPQPHOSIDA21081558
Sequence
(Fasta)		MKEQPLKEIT QLIHAIKVGL VEGSYNITNK TLDIFKYIIM SKSWQNADAL MQIVRDQCKI 60
LQAALPQETV TSNIARRILK LTREEFDLLH AKVQHFADDS QASLSLHKLV TQTSESNVSV 120
DYSVPQHGLR EALLDHLQEV ETELETSSEN ICVQAEEHIH SSEIILTLGH SRSVENFLKR 180
AIKKRQFLTI IVAECAPACR GHNLAASLAN EKNVEIVVIP DAAIFAMMSR VNKVIIGTHS 240
VLANGGLRAA CGAYTVALAA KHYSVPVIVL APMYKLSPLH LCEQDAFNMV GCAEDVIPYD 300
SIPAREAKVY SPMFDYVPPE LVTLFISNTG GHAPSYVYRL LTELYHPEDL EI 353
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0396--Initiation factor
KW-0413--Isomerase
KW-0648--Protein biosynthesis
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR000649--IF-2B-related
PROSITE
Pfam

PF01008--IF-2B
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005851--C:eukaryotic translation initiation factor 2B complex
GO:0005085--F:guanyl-nucleotide exchange factor activity
GO:0016853--F:isomerase activity
GO:0003743--F:translation initiation factor activity
GO:0071456--P:cellular response to hypoxia
GO:0043547--P:positive regulation of GTPase activity
GO:0006446--P:regulation of translational initiation
GO:0006413--P:translational initiation