dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0002964
Uniprot Accession O76511; TYSY_DROME; Q9VQJ3;
Genbank Protein ID NP_001285570.1; NP_477367.1;
Genbank Nucleotide ID NM_001298641.1; NM_058019.4;
Protein Name Thymidylate synthase
Protein Synonyms/Alias
Gene Name Ts
Gene Synonyms/Alias CG3181;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 8
PositionPeptidesSourceReferences ( PMIDs )
4----MVLTPTKDGPDPHOSIDA;PhosphoPep 2.021081558; 19060867
14KDGPDQESMPLPADNPHOSIDA;PhosphoPep 2.0;curated21081558; 19060867; 22817900
24LPADNGESPSKQQAPdbPTM 3.0;Phospho.ELM 9.0;PHOSIDA;PhosphoPep 2.0;UniProt;curated18327897; 16381945; 23193290; 21081558; 19060867; 22817900
26ADNGESPSKQQAPVNdbPTM 3.0;Phospho.ELM 9.0;PHOSIDA;PhosphoPep 2.0;UniProt;curated18327897; 16381945; 23193290; 21081558; 19060867; 22817900
39VNRDEMHYLDLLRHIdbPTM 3.0;Phospho.ELM 9.0;UniProt18327897; 16381945; 23193290
119VHIWDGNSSREFLDKPHOSIDA;curated21081558; 22817900
208CHCLAQFYVSEKRGEdbPTM 3.0;UniProt17372656; 16381945; 23193290
210CLAQFYVSEKRGELSdbPTM 3.0;UniProt17372656; 16381945; 23193290
Sequence
(Fasta)		MVLTPTKDGP DQESMPLPAD NGESPSKQQA PVNRDEMHYL DLLRHIIANG EQRMDRTEVG 60
TLSVFGSQMR FDMRNSFPLL TTKRVFFRAV AEELLWFVAG KTDAKLLQAK NVHIWDGNSS 120
REFLDKMGFT GRAVGDLGPV YGFQWRHFGA QYGTCDDDYS GKGIDQLRQV IDTIRNNPSD 180
RRIIMSAWNP LDIPKMALPP CHCLAQFYVS EKRGELSCQL YQRSADMGLG VPFNIASYAL 240
LTHMIAHVTG LKPGDFVHTM GDTHVYLNHV EPLKEQLERT PRPFPKLIIK RQVQDIEDFR 300
FEDFQIVDYN PHPKIQMDMA V 322
Keyword

KW-0181--Complete proteome
KW-0489--Methyltransferase
KW-0545--Nucleotide biosynthesis
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0808--Transferase
Interpro

IPR023451--Thymidate_synth/dCMP_Mease
IPR000398--Thymidylate_synthase
IPR020940--Thymidylate_synthase_AS
PROSITE

PS00091--THYMIDYLATE_SYNTHASE
Pfam

PF00303--Thymidylat_synt
Gene Ontology

GO:0004799--F:thymidylate synthase activity
GO:0006231--P:dTMP biosynthetic process
GO:0006235--P:dTTP biosynthetic process
GO:0022008--P:neurogenesis