dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0002453
Uniprot Accession O74302; YD13A_YEAST; D6VSP5;
Genbank Protein ID NP_058149.1;
Genbank Nucleotide ID NM_001184420.1;
Protein Name Transposon Ty1-DR4 Gag polyprotein
Protein Synonyms/Alias Gag-p49;Transposon Ty1 protein A;TY1A;TYA;p58;
Gene Name TY1A-DR4
Gene Synonyms/Alias YDRCTy1-3 GAG;YDR261C-C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA has also nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity).
Phosphorylation Sites
 dbPAF PTMs: 15
PositionPeptidesSourceReferences ( PMIDs )
3-----MESQQLSQHScurated19823750; 20377248
7-MESQQLSQHSPISHPhosphoGRID 2.0;PHOSIDA;curated19823750; 19795423; 21081558; 26040289; 22369663; 22817900;
10SQQLSQHSPISHGSAPhosphoGRID 2.0;SysPTM 2.0;curated19779198; 18407956; 19366988; 15665377; 26040289; 22369663;
13LSQHSPISHGSACASPhosphoGRID 2.0;SysPTM 2.0;curated15665377; 19366988; 26040289; 22369663; 22817900; 23607784;
16HSPISHGSACASVTSPhosphoGRID 2.0;SysPTM 2.0;curated18407956; 19366988; 26040289; 23607784
20SHGSACASVTSKEVHSysPTM 2.0;curated18407956; 19366988; 26040289
23SACASVTSKEVHTNQSysPTM 2.0;curated18407956; 19366988; 19823750
28VTSKEVHTNQDPLDVSysPTM 2.018407956; 19366988
36NQDPLDVSASKTEECPhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated18407956; 19779198; 19060867; 19366988; 26040406; 22817900;
38DPLDVSASKTEECEKPhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated21177495; 19779198; 17330950; 19060867; 19366988; 26040406;
40LDVSASKTEECEKASPhosphoPep 2.0;curated19060867; 23825934
47TEECEKASTKANSQQPhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated21177495; 19779198; 17330950; 19060867; 17287358; 19366988;
48EECEKASTKANSQQTPhosphoGRID 2.0;PhosphoPep 2.0;curated21177495; 19060867; 22817900; 24961812
71PENPHHASPQPASVPPhosphoGRID 2.0;PhosphoPep 2.0;curated18407956; 19060867; 22817900
439DLHLRPETY------curated24961812
Sequence
(Fasta)		MESQQLSQHS PISHGSACAS VTSKEVHTNQ DPLDVSASKT EECEKASTKA NSQQTTTPAS 60
SAVPENPHHA SPQPASVPPP QNGPYPQQCM MTQNQANPSG WSFYGHPSMI PYTPYQMSPM 120
YFPPGPQSQF PQYPSSVGTP LSTPSPESGN TFTDSSSADS DMTSTKKYVR PPPMLTSPND 180
FPNWVKTYIK FLQNSNLGGI IPTVNGKPVR QITDDELTFL YNTFQIFAPS QFLPTWVKDI 240
LSVDYTDIMK ILSKSIEKMQ SDTQEANDIV TLANLQYNGS TPADAFETKV TNIIDRLNNN 300
GIHINNKVAC QLIMRGLSGE YKFLRYTRHR HLNMTVAELF LDIHAIYEEQ QGSRNSKPNY 360
RRNPSDEKND SRSYTNTTKP KVIARNPQKT NNSKSKTARA HNVSTSNNSP STDNDSISKS 420
TTEPIQLNNK HDLHLRPETY 441
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0688--Ribosomal frameshifting
KW-0694--RNA-binding
KW-0814--Transposable element
Interpro

IPR015820--Retrotransposon_Ty1A_N
PROSITE
Pfam

PF01021--TYA
Gene Ontology

GO:0005737--C:cytoplasm
GO:0000943--C:retrotransposon nucleocapsid
GO:0003723--F:RNA binding
GO:0032197--P:transposition, RNA-mediated