dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0002442
Uniprot Accession O70593; SGTA_RAT; Q548F5;
Genbank Protein ID NP_073194.1;
Genbank Nucleotide ID NM_022703.3;
Protein Name Small glutamine-rich tetratricopeptide repeat-containing protein alpha
Protein Synonyms/Alias Alpha-SGT;Small glutamine-rich protein with tetratricopeptide repeats 1;
Gene Name Sgta
Gene Synonyms/Alias Sgt;Sgt1;Stg;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)		 Co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity.
Phosphorylation Sites
 dbPAF PTMs: 6
PositionPeptidesSourceReferences ( PMIDs )
81DPRGPDRTPPSEEDSdbPTM 3.0;PhosphoSitePlus;SysPTM 2.0;UniProt;curated16641100; 16381945; 23193290; 19700791; 22135298; 19366988;
84GPDRTPPSEEDSAEAPhosphoSitePlus;UniProt;curated22135298; 22673903; 21630457; 23984901
88TPPSEEDSAEAERLKcurated23712012; 21630457
302IRSQVVRSRTPSASHPhosphoSitePlus;curated22135298; 21630457
304SQVVRSRTPSASHEEPhosphoSitePlus22135298
306VVRSRTPSASHEEQQPhosphoSitePlus;curated22135298; 23712012; 21630457; 23984901
Sequence
(Fasta)		MDNRKRLAYA IIQFLHGQLR HGGLSSDAQE SLEVAIQCLE TAFGVTLEDS DLALPQTLPE 60
IFEAATASKE MPQDPRGPDR TPPSEEDSAE AERLKTEGNE QMKLENFEAA VHLYGKAIEL 120
NPANAVYFCN RAAAYSKLGN YVGAVQDCER AIGIDPGYSK AYGRMGLALS SLNKHAEAVA 180
YYKKALELDP DNDTYKSNLK IAELKLREAP SPTGGVGSLD IAGLLNNPHF ITMASSLMNS 240
PQLQQLMSGM ISGGHNPLGT PGSSPQHSDL ASLIQAGQQF AQQMQQQNPE FVEQIRSQVV 300
RSRTPSASHE EQQE 315
Keyword

KW-0007--Acetylation
KW-0143--Chaperone
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0802--TPR repeat
Interpro

IPR032374--SGTA_dimer
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR001440--TPR_1
IPR019734--TPR_repeat
PROSITE

PS50005--TPR
PS50293--TPR_REGION
Pfam

PF16546--SGTA_dimer
PF00515--TPR_1
PF13414--TPR_11
Gene Ontology

GO:0005829--C:cytosol
GO:0016020--C:membrane
GO:1903071--P:positive regulation of ER-associated ubiquitin-dependent protein catabolic process