dbPAF Protein Information
| Tag | Content | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0002428 | ||||||||
| Uniprot Accession | O70521; RGS19_RAT; | ||||||||
| Genbank Protein ID | NP_067693.1; | ||||||||
| Genbank Nucleotide ID | NM_021661.2; | ||||||||
| Protein Name | Regulator of G-protein signaling 19 | ||||||||
| Protein Synonyms/Alias | |||||||||
| Gene Name | Rgs19 | ||||||||
| Gene Synonyms/Alias | Gaip; | ||||||||
| Organism | Rattus norvegicus(Rat) | ||||||||
| NCBI Taxa ID | 10116 | ||||||||
| Functional Description (View all) |
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, predominantly to G(i)-alpha-3. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein (By similarity). | ||||||||
| Phosphorylation Sites |
dbPAF PTMs: 1
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| Sequence (Fasta) | MPTPHEAEKQ HTGPEEADRP PSMSSHDAAP SGPPSRNPCC LCWCCCCSCS WNQERQRAWQ 60 VSRESKLQPL PSCEVCTPPS PEEVQSWAQS FDKLMHSPTG RSVFRAFLRT EYSEENMLFW 120 LACEELKTEA DRHVVDEKAR LIYEDYVSIL SPKEVSLDSR VREGINRKMQ EPSPHTFDDA 180 QLQIYTLMHR DSYPRFLTSP TYRSLLLQGA PQSSEA 217 |
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| Keyword | KW-0181--Complete proteome |
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| Interpro | |||||||||
| PROSITE | PS50132--RGS |
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| Pfam | PF00615--RGS |
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| Gene Ontology | GO:0005903--C:brush border |