dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0002394
Uniprot Accession O70377; SNP23_RAT; A0JPL8;
Genbank Protein ID NP_073180.1;
Genbank Nucleotide ID NM_022689.2;
Protein Name Synaptosomal-associated protein 23
Protein Synonyms/Alias
Gene Name Snap23
Gene Synonyms/Alias
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion.
Phosphorylation Sites
dbPAF PTMs: 10
PositionPeptidesSourceReferences ( PMIDs )
5---MDDLSPEEIQLRPhosphoSitePlus22135298
20AHQVTDESLESTRRIPhosphoSitePlus22135298
24TDESLESTRRILGLAdbPTM 3.0;PhosphoSitePlus;curated20967886; 16381945; 23193290; 22135298; 23712012
95NRTKNFESGKNYKATdbPTM 3.0;PhosphoSitePlus15611044; 20967886; 16381945; 23193290; 22135298
109TWGDGGDSSPSNVVSPhosphoSitePlus;curated22135298; 23589303
110WGDGGDSSPSNVVSKdbPTM 3.0;PhosphoSitePlus;SysPTM 2.0;curated16641100; 17683130; 19700791; 20967886; 16381945; 23193290;
116SSPSNVVSKQPSRITdbPTM 3.0;PhosphoSitePlus;SysPTM 2.016641100; 16381945; 23193290; 22135298; 19366988
120NVVSKQPSRITNGQPdbPTM 3.0;PhosphoSitePlus15611044; 20967886; 16381945; 23193290; 22135298
123SKQPSRITNGQPQQTcurated23984901
160ENLTQVGSILGNLKNdbPTM 3.0;PhosphoSitePlus;curated20967886; 16381945; 23193290; 22135298; 23984901
Sequence
(Fasta)
MDDLSPEEIQ LRAHQVTDES LESTRRILGL AIESQDAGIK TITMLDEQGE QLNRIEEGMD 60
QINKDMREAE KTLTELNKCC GLCVCPCNRT KNFESGKNYK ATWGDGGDSS PSNVVSKQPS 120
RITNGQPQQT TGAASGGYIK RITNDAREDE MEENLTQVGS ILGNLKNMAL DMGNEIDAQN 180
QQIQKITEKA DTNKNRIDIA NTRAKKLIDS 211
Keyword

KW-0007--Acetylation
KW-0965--Cell junction
KW-1003--Cell membrane
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0968--Cytoplasmic vesicle
KW-0903--Direct protein sequencing
KW-0449--Lipoprotein
KW-0472--Membrane
KW-0564--Palmitate
KW-0597--Phosphoprotein
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0770--Synapse
KW-0771--Synaptosome
KW-0813--Transport

Interpro

IPR000928--SNAP-25
IPR000727--T_SNARE_dom

PROSITE

PS50192--T_SNARE

Pfam

PF00835--SNAP-25

Gene Ontology

GO:0030054--C:cell junction
GO:0030659--C:cytoplasmic vesicle membrane
GO:0005886--C:plasma membrane
GO:0031201--C:SNARE complex
GO:0043195--C:terminal bouton
GO:0005484--F:SNAP receptor activity
GO:0019905--F:syntaxin binding
GO:0006887--P:exocytosis
GO:0061025--P:membrane fusion
GO:0006461--P:protein complex assembly
GO:0015031--P:protein transport
GO:0017157--P:regulation of exocytosis
GO:0031629--P:synaptic vesicle fusion to presynaptic membrane
GO:0016082--P:synaptic vesicle priming
GO:0016192--P:vesicle-mediated transport