dbPAF Protein Information
| Tag | Content |
|---|---|
| dbPAF ID | dbPAF-0002370 |
| Uniprot Accession | O70277; TRIM3_RAT; |
| Genbank Protein ID | NP_113974.1; |
| Genbank Nucleotide ID | NM_031786.1; |
| Protein Name | Tripartite motif-containing protein 3 |
| Protein Synonyms/Alias | Brain-expressed RING finger protein;RING finger protein 22; |
| Gene Name | Trim3 |
| Gene Synonyms/Alias | Berp;Rnf22; |
| Organism | Rattus norvegicus(Rat) |
| NCBI Taxa ID | 10116 |
| Functional Description (View all) |
Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation (By similarity). |
| Phosphorylation Sites |
dbPAF PTMs: 4 |
| Sequence (Fasta) | MAKREDSPGP EVQPMDKQFL VCSICLDRYR CPKVLPCLHT FCERCLQNYI PPQSLTLSCP 60 VCRQTSILPE QGVSALQNNF FISSLMEAMQ QAPDGAHDPE DPHPLSAVAG RPLSCPNHEG 120 KTMEFYCEAC ETAMCGECRA GEHREHGTVL LRDVVEQHKA ALQRQLEAVR GRLPQLSAAI 180 ALVGGISQQL QERKAEALAQ ISAAFEDLEQ ALQQRKQALV SDLESICGAK QKVLQTQLDT 240 LRQGQEHIGS SCSFAEQALR LGSAPEVLLV RKHMRERLAA LAAQAFPERP HENAQLELVL 300 EVDGLRRSVL NLGALLTTSA AAHETVATGE GLRQALVGQP ASLTVTTKDK DGRLVRTGSA 360 ELCAEITGPD GMRLAVPVVD HKNGTYELVY TARTEGDLLL SVLLYGQPVR GSPFRVRALR 420 PGDLPPSPDD VKRRVKSPGG PGSHVRQKAV RRPSSMYSTG GKRKDNPIVD ELVFRVGSRG 480 REKGEFTNLH PLSAASSGRI VVADSNNQCI QVFSNEGQFK FRFGVRGRSP GQLQRPTGVA 540 VDTNGDIIVA DYDNRWVSIF SPEGKFKTKI GAGRLMGPKG VAVDRNGHII VVDNKSCCVF 600 TFQPNGKLVG RFGGRGATDR HFAGPHFVAV NNKNEIVVTD FHNHSVKVYS ADGEFLFKFG 660 SHGEGNGQFN APTGVAVDSN GNIIVADWGN SRIQVFDSSG SFLSYINTSA EPLYGPQGLA 720 LTSDGHVVVA DAGNHCFKAY RYLQ 745 |
| Keyword | KW-0007--Acetylation |
| Interpro | IPR011042--6-blade_b-propeller_TolB-like |
| PROSITE | PS50194--FILAMIN_REPEAT |
| Pfam | PF00630--Filamin |
| Gene Ontology | GO:0005737--C:cytoplasm |