dbPAF Protein Information
| Tag | Content |
|---|---|
| dbPAF ID | dbPAF-0002361 |
| Uniprot Accession | O70248; APBA3_RAT; B1WBQ3; |
| Genbank Protein ID | NP_113969.1; XP_006241082.1; |
| Genbank Nucleotide ID | NM_031781.1; XM_006241020.2; |
| Protein Name | Amyloid beta A4 precursor protein-binding family A member 3 |
| Protein Synonyms/Alias | Adapter protein X11gamma;Neuron-specific X11L2 protein;Neuronal Munc18-1-interacting protein 3;Mint-3; |
| Gene Name | Apba3 |
| Gene Synonyms/Alias | Mint3; |
| Organism | Rattus norvegicus(Rat) |
| NCBI Taxa ID | 10116 |
| Functional Description (View all) |
May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP. May enhance the activity of HIF1A in macrophages by inhibiting the activity of HIF1AN (By similarity). |
| Phosphorylation Sites |
dbPAF PTMs: 3 |
| Sequence (Fasta) | MEFLPEPQHP PGPPTMDLEE PKGPEVPSED HPSNTQWALG PRGPDTLSEM ELDTSSVRAL 60 VQQLEALPSD LGGQFPDGAP CPLHIATGQG LATQENLDAG GLLSAEAGGD NLLGLLRCEA 120 SLPAQSVPPD PAQAAPRLLQ PPEDPGGDPG WMEGTEPADN RSSSSSPELW LETAPLVTHR 180 DPPVGTQSQE TLASCPAVSE VPGPCGQEEL MDGVLFGAKY LGSTQLLSER NPPPSTRMGQ 240 AQEAMDRVKA PEGETQPMTE VDIFISTKRV KVLAADSQDA LMDHALQTIS YIADIGPVLV 300 LMARRRLAKR TTSQDRQRQL YKMLCHVFHS EDAQLIAQAI GQAFSIAYSQ FLQENRIDPS 360 QVGMQPSASA SHPHNGDLDH FCNSQNCREV CIQKRPGEGL GVALVESGWG SLLPTAVIAN 420 LLHGGPAERC GALSIGDRVT AINGTSLVGL SLAACQAAVR EVRRHSSVTL SIIHCPPVTT 480 AVIHRPHVRE QLGFCVENGI ICSLLRGSAA ERGGVRVGHR IIEVNGQSVV AMPHARIIQL 540 LTETREIHIK TMPAATYRLL TGQEQPVYL |
| Keyword | KW-0007--Acetylation |
| Interpro | IPR030531--Apba3 |
| PROSITE | |
| Pfam | |
| Gene Ontology | GO:0048471--C:perinuclear region of cytoplasm |