dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0002337
Uniprot Accession O70150; KCC1B_RAT; O08767;
Genbank Protein ID NP_058971.1; XP_006229635.1; XP_006229636.1; XP_006229637.1; XP_008771850.1; XP_008771851.1;
Genbank Nucleotide ID NM_017275.1; XM_006229573.2; XM_006229574.2; XM_006229575.2; XM_008773628.1; XM_008773629.1;
Protein Name Calcium/calmodulin-dependent protein kinase type 1B
Protein Synonyms/Alias CaM kinase I beta;CaM kinase IB;CaM-KI beta;CaMKI-beta;Pregnancy up-regulated non-ubiquitously-expressed CaM kinase homolog;
Gene Name Pnck
Gene Synonyms/Alias
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)		 Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro, isoform 1 and isoform 2 phosphorylate CREB1, SYN1/synapsin I. Phosphorylates and activates CAMK1.
Phosphorylation Sites
 dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
305KRAFNATSFLRHIRKPhosphoSitePlus22135298
Sequence
(Fasta)		MLLLKKQTED ISSVYEIREK LGSGAFSEVM LAQERGSAHL VALKCIPKKA LRGKEALVEN 60
EIAVLRRISH PNIVALEDVH ESPSHLYLAM ELVTGGELFD RIMERGSYTE KDASHLVGQV 120
LGAVSYLHSL GIVHRDLKPE NLLYATPFED SKIMVSDFGL SKIQAGNMLG TACGTPGYVA 180
PELLEQKPYG KAVDVWALGV ISYILLCGYP PFYDESDPEL FSQILRASYE FDSPFWDDIS 240
ESAKDFIRHL LERDPQKRFT CQQALQHLWI SGDAALDRDI LGSVSEQIQK NFARTHWKRA 300
FNATSFLRHI RKLGQSPEGE EASRQGMTRH SHPGLGTSQS PKW 344
Keyword

KW-0025--Alternative splicing
KW-0067--ATP-binding
KW-0106--Calcium
KW-0112--Calmodulin-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
Interpro

IPR020636--Ca/CaM-dep_Ca-dep_prot_Kinase
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR002290--Ser/Thr_dual-sp_kinase
IPR008271--Ser/Thr_kinase_AS
PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
Pfam

PF00069--Pkinase
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0004683--F:calmodulin-dependent protein kinase activity