dbPAF Protein Information
| Tag | Content | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0002333 | ||||||||||||
| Uniprot Accession | O70142; SHC2_RAT; | ||||||||||||
| Genbank Protein ID | NP_001101535.1; | ||||||||||||
| Genbank Nucleotide ID | NM_001108065.1; | ||||||||||||
| Protein Name | SHC-transforming protein 2 | ||||||||||||
| Protein Synonyms/Alias | Protein Sck;SH2 domain protein C2;Src homology 2 domain-containing-transforming protein C2; | ||||||||||||
| Gene Name | Shc2 | ||||||||||||
| Gene Synonyms/Alias | Sck; | ||||||||||||
| Organism | Rattus norvegicus(Rat) | ||||||||||||
| NCBI Taxa ID | 10116 | ||||||||||||
| Functional Description (View all) |
Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons (By similarity). | ||||||||||||
| Phosphorylation Sites |
dbPAF PTMs: 2
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| Sequence (Fasta) | MTQGPGGRAA PEPEAPTTFC ALLPRMPQWK FAAPGSFLGR GPAAARVAGA AEAQPEPGVP 60 ALAAVLGACE PRCAAPCPLP ALGRCRGSGS RGARGTPDVA DEWVRKGGFI HKPAHGWLHP 120 DARVLGPGVS YIVRYMGCIE VLRSMRSLDF NTRTQVTREA INRLHEAVPG VRGSWKKKAP 180 NKALASILGK SNLRFAGMSI SVNISVDGLN LSVPATRQII ANHHMQSISF ASGGDTDMTD 240 YVAYVAKDPI NQRACHILEC CEGLAQSVIS TVGQAFELRF KQYLHSPPKA VVPPERLTGL 300 EESAWGDGEV TADHDYYNSI PGKEPPLGGL VDSRLAVTQP CALTTLGGLG QGLSPAWRDV 360 RGLPWDMGPS GAVPPGDGYV QADARGPHDY EEHLYVNTQG LDALELEDTS ETPLQPEDSP 420 KKDLFDMRPF EDALKLHECS VAAGITAASL PLEDQWPSPP TRRAPIAPTE EQLRQEPWYH 480 GRMSRRAAEK LLRADGDFLV RDSITNPGQY VLTGMHAGQP KHLLLVDPEG VVRTKDVLFE 540 SISHLIDYHL KNGLPIVAAE SELHLRGVVS REP 574 |
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| Keyword | KW-0181--Complete proteome |
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| Interpro | IPR011993--PH/PTB_dom |
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| PROSITE | |||||||||||||
| Pfam | |||||||||||||
| Gene Ontology | GO:0005622--C:intracellular |