dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0002326
Uniprot Accession O62619; KPYK_DROME; C3KGI0; Q86PE3; Q8MT14; Q9VD24;
Genbank Protein ID NP_524448.3; NP_732723.1;
Genbank Nucleotide ID NM_079724.3; NM_170004.2;
Protein Name Pyruvate kinase
Protein Synonyms/Alias
Gene Name PyK
Gene Synonyms/Alias CG7070;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 8
PositionPeptidesSourceReferences ( PMIDs )
40MCRLQFDSPVPHVRLPHOSIDA;PhosphoPep 2.0;SysPTM 2.0;curated21081558; 19060867; 18327897; 19366988; 22817900
58VCTIGPASSSVEMLEcurated22817900
59CTIGPASSSVEMLEKcurated22817900
60TIGPASSSVEMLEKMcurated22817900
336CATQMLESMVKKPRPcurated22817900
407DLVRGAGTIDASHAAPhosphoPep 2.019060867
411GAGTIDASHAAAIAAPhosphoPep 2.0;curated19060867; 22817900
521VTGWKQGSGFTNTIRPhosphoPep 2.0;curated19060867; 22817900
Sequence
(Fasta)		MVNVTIYDEA PQLKPNEVPQ NMAAGADTQL EHMCRLQFDS PVPHVRLSGI VCTIGPASSS 60
VEMLEKMMAT GMNIARMNFS HGSHEYHAAT VANVRQAVKN YSAKLGYEHP VAIALDTKGP 120
EIRTGLIGGS GTAEIELKKG EKIKLTTNKE FLEKGSLEIV YVDYENIVNV VKPGNRVFVD 180
DGLISLIVRE VGKDSLTCEV ENGGSLGSRK GVNLPGVPVD LPAVSEKDKS DLLFGVEQEV 240
DMIFASFIRN AAALTEIRKV LGEKGKNIKI ISKIENQQGM HNLDEIIEAG DGIMVARGDL 300
GIEIPAEKVF LAQKAMIARC NKAGKPVICA TQMLESMVKK PRPTRAEISD VANAVLDGAD 360
CVMLSGETAK GEYPLECVLT MAKTCKEAEA ALWHQNLFND LVRGAGTIDA SHAAAIAAVE 420
AATKAKASAI VVITTSGKSA FQVSKYRPRC PIIAVTRFAQ TARQAHLYRG LVPLIYKEPG 480
LGDWLKDVDV RVQFGLQVGK KNGFIKTGDS VVVVTGWKQG SGFTNTIRIV TVE 534
Keyword

KW-0025--Alternative splicing
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0324--Glycolysis
KW-0418--Kinase
KW-0460--Magnesium
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-0630--Potassium
KW-0670--Pyruvate
KW-1185--Reference proteome
KW-0808--Transferase
Interpro

IPR001697--Pyr_Knase
IPR015813--Pyrv/PenolPyrv_Kinase-like_dom
IPR011037--Pyrv_Knase-like_insert_dom
IPR015794--Pyrv_Knase_a/b
IPR018209--Pyrv_Knase_AS
IPR015793--Pyrv_Knase_brl
IPR015795--Pyrv_Knase_C
IPR015806--Pyrv_Knase_insert_dom
PROSITE

PS00110--PYRUVATE_KINASE
Pfam

PF00224--PK
PF02887--PK_C
Gene Ontology

GO:0005829--C:cytosol
GO:0005811--C:lipid particle
GO:0043186--C:P granule
GO:0005524--F:ATP binding
GO:0016301--F:kinase activity
GO:0000287--F:magnesium ion binding
GO:0030955--F:potassium ion binding
GO:0004743--F:pyruvate kinase activity
GO:0006096--P:glycolytic process
GO:0007520--P:myoblast fusion
GO:0006090--P:pyruvate metabolic process
GO:0009744--P:response to sucrose
GO:0007525--P:somatic muscle development