| Tag |
Content |
| dbPAF ID |
dbPAF-0002324 |
| Uniprot Accession |
O62609; O62609_DROME;
|
| Genbank Protein ID |
NP_524610.1; NP_733439.2;
|
| Genbank Nucleotide ID |
NM_079871.4; NM_170560.2;
|
| Protein Name |
Mothers against decapentaplegic homolog |
| Protein Synonyms/Alias |
|
| Gene Name |
Med |
| Gene Synonyms/Alias |
Medea;CG1775;Dmel_CG1775; |
| Organism |
Drosophila melanogaster(Fruit fly) |
| NCBI Taxa ID |
7227 |
Functional Description
(View all) |
|
Phosphorylation Sites
|
dbPAF PTMs: 2 |
Sequence
(Fasta) | MGGGSGACPP AHMYGAVAPQ DIIVRDMVQM PPPPSNAPTS ADACLSIVHS LMCHRQGGES 60
EGFAKRAIES LVKKLKEKRD ELDSLITAIT TNGAHPSKCV TIQRTLDGRL QVAGRKGFPH 120
VIYARIWRWP DLHKNELKHV KYCAFAFDLK CDSVCVNPYH YERVVSPGID LSGLSLQSGP 180
SRLVKDEYSA GPLVGSMDID GNDIGTIQHH PTQMVGPGGY GYPQGPSEYV GDANPMSAMF 240
PTGRTIPKIE PQDGVAGSRG SWMVPPPPRL GQPPQQQQQQ PQQQTPQPTQ QQQAQSQAAA 300
HSLPVPHGMP GMPGPMNPGP VMAPPPPPQQ AQNPQGNGVH HTQANSPTDP ASALAMQQQQ 360
QQQQQQQQQQ QQQQQQSGGV PNGSVNAGGG AAAGGQYYGQ PPPVSQMQGA GGGGTSVAPS 420
VHAQQNGYVS QPGSAGSAPV GGGGVFGTAQ PTPQQPQQPP TGVQANTGSA GAQAGAGGGA 480
AGTWTGPNTL TYTQSMQPPD PRSLPGGFWN SSLSGDLGSP QQTPPQQQQQ QQQPRLLSRQ 540
PPPEYWCSIA YFELDTQVGE TFKVPSAKPN VIIDGYVDPS GGNRFCLGAL SNVHRTEQSE 600
RARLHIGKGV QLDLRGEGDV WLRCLSDNSV FVQSYYLDRE AGRTPGDAVH KIYPAACIKV 660
FDLRQCHQQM HSLATNAQAA AAAQAAAVAG VANQQMGGGG RSMTAAAGIG VDDLRRLCIL 720
RLSFVKGWGP DYPRQSIKET PCWIEVHLHR ALQLLDEVLH AMPIDGPRAA A
772Fasta Sequence
>O62609|Med|Drosophila melanogaster(Fruit fly)
MGGGSGACPPAHMYGAVAPQDIIVRDMVQMPPPPSNAPTSADACLSIVHSLMCHRQGGESEGFAKRAIESLVKKLKEKRDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARIWRWPDLHKNELKHVKYCAFAFDLKCDSVCVNPYHYERVVSPGIDLSGLSLQSGPSRLVKDEYSAGPLVGSMDIDGNDIGTIQHHPTQMVGPGGYGYPQGPSEYVGDANPMSAMFPTGRTIPKIEPQDGVAGSRGSWMVPPPPRLGQPPQQQQQQPQQQTPQPTQQQQAQSQAAAHSLPVPHGMPGMPGPMNPGPVMAPPPPPQQAQNPQGNGVHHTQANSPTDPASALAMQQQQQQQQQQQQQQQQQQQQSGGVPNGSVNAGGGAAAGGQYYGQPPPVSQMQGAGGGGTSVAPSVHAQQNGYVSQPGSAGSAPVGGGGVFGTAQPTPQQPQQPPTGVQANTGSAGAQAGAGGGAAGTWTGPNTLTYTQSMQPPDPRSLPGGFWNSSLSGDLGSPQQTPPQQQQQQQQPRLLSRQPPPEYWCSIAYFELDTQVGETFKVPSAKPNVIIDGYVDPSGGNRFCLGALSNVHRTEQSERARLHIGKGVQLDLRGEGDVWLRCLSDNSVFVQSYYLDREAGRTPGDAVHKIYPAACIKVFDLRQCHQQMHSLATNAQAAAAAQAAAVAGVANQQMGGGGRSMTAAAGIGVDDLRRLCILRLSFVKGWGPDYPRQSIKETPCWIEVHLHRALQLLDEVLHAMPIDGPRAAA
|
| Keyword |
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0238--DNA-binding
KW-0539--Nucleus
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
|
| Interpro |
IPR013790--Dwarfin
IPR003619--MAD_homology1_Dwarfin-type
IPR013019--MAD_homology_MH1
IPR017855--SMAD_dom-like
IPR001132--SMAD_dom_Dwarfin-type
IPR008984--SMAD_FHA_domain
|
| PROSITE |
PS51075--MH1
PS51076--MH2
|
| Pfam |
PF03165--MH1
PF03166--MH2
|
| Gene Ontology |
GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005667--C:transcription factor complex
GO:0003677--F:DNA binding
GO:0043565--F:sequence-specific DNA binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0030616--F:transforming growth factor beta receptor, common-partner cytoplasmic mediator activity
GO:0030509--P:BMP signaling pathway
GO:0008283--P:cell proliferation
GO:0009950--P:dorsal/ventral axis specification
GO:0009953--P:dorsal/ventral pattern formation
GO:0042078--P:germ-line stem cell division
GO:0030718--P:germ-line stem cell population maintenance
GO:0007507--P:heart development
GO:0007480--P:imaginal disc-derived leg morphogenesis
GO:0007476--P:imaginal disc-derived wing morphogenesis
GO:0035556--P:intracellular signal transduction
GO:0045705--P:negative regulation of salivary gland boundary specification
GO:0048666--P:neuron development
GO:0030707--P:ovarian follicle cell development
GO:0045887--P:positive regulation of synaptic growth at neuromuscular junction
GO:0006355--P:regulation of transcription, DNA-templated
GO:0031290--P:retinal ganglion cell axon guidance
GO:0035019--P:somatic stem cell population maintenance
GO:0006351--P:transcription, DNA-templated
GO:0007179--P:transforming growth factor beta receptor signaling pathway
|
