dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0002322
Uniprot Accession O62531; O62531_DROME;
Genbank Protein ID NP_649906.1;
Genbank Nucleotide ID NM_141649.2;
Protein Name Adaptor protein complex 1, mu subunit
Protein Synonyms/Alias
Gene Name AP-1mu
Gene Synonyms/Alias AP-47;AP47;CG9388;Dmel_CG9388;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
156PRIPVAVTNAVSWRSPhosphoPep 2.0;curated19060867; 22817900
225DKVLFESTGRGKSKScurated22817900
Sequence
(Fasta)
MSSSAIFVLD VKGKVLISRN YRGDNIDMAV IDKFMPLLME REEEGLITPI LQTAETTFAY 60
IKTNNLYIVS TTPRNKNVNI ALVFVFLHKI AQVFVEYFKE LEEESIRDNF VIIYELLDEL 120
LDFGYPQTTD SKILQEYITQ EGHKLELQPR IPVAVTNAVS WRSEGIKYRK NEVFLDVIES 180
VNLLANANGN VLRSEIVGAI KMRVYLSGMP ELRLGLNDKV LFESTGRGKS KSVELEDVKF 240
HQCVRLSRFE NDRTISFIPP DGEFELMSYR LNTHVKPLIW IESVIERHAH SRVEYMIKAK 300
SQFKRRSTAN NVEIVIPVPA DADSPKFKTT IGSCKYAPEQ NAIIWTIKSF PGGKEYLMRA 360
HFGLPSVESE DNTEGKPPIQ VRFEIPYFTT SGIQVRYLKI IEKSGYQALP WVRYITQNGD 420
YQLRTN 427
Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0653--Protein transport
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0813--Transport

Interpro

IPR022775--AP_mu_sigma_su
IPR001392--Clathrin_mu
IPR018240--Clathrin_mu_CS
IPR011012--Longin-like_dom
IPR028565--MHD

PROSITE

PS00990--CLAT_ADAPTOR_M_1
PS00991--CLAT_ADAPTOR_M_2
PS51072--MHD

Pfam

PF00928--Adap_comp_sub
PF01217--Clat_adaptor_s

Gene Ontology

GO:0030121--C:AP-1 adaptor complex
GO:0035976--C:AP1 complex
GO:0030136--C:clathrin-coated vesicle
GO:0030135--C:coated vesicle
GO:0008021--C:synaptic vesicle
GO:0030276--F:clathrin binding
GO:0008565--F:protein transporter activity
GO:0048749--P:compound eye development
GO:0006886--P:intracellular protein transport
GO:0046907--P:intracellular transport
GO:2001136--P:negative regulation of endocytic recycling
GO:0045746--P:negative regulation of Notch signaling pathway
GO:0007269--P:neurotransmitter secretion
GO:0033363--P:secretory granule organization
GO:0016183--P:synaptic vesicle coating
GO:0006901--P:vesicle coating
GO:0016192--P:vesicle-mediated transport