dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0002265
Uniprot Accession O61613; NMT_DROME; Q9XZ55;
Genbank Protein ID NP_523969.1;
Genbank Nucleotide ID NM_079245.3;
Protein Name Glycylpeptide N-tetradecanoyltransferase
Protein Synonyms/Alias Myristoyl-CoA:protein N-myristoyltransferase;NMT;Peptide N-myristoyltransferase;dNMT;
Gene Name Nmt
Gene Synonyms/Alias CG7436;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)
Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
295SHLARNMTMQRTMKLPHOSIDA;curated21081558; 22817900
Sequence
(Fasta)
MPNENAEDLS GQELKQKAKE VADASEAMLE KVVAGLNIQD TASTNAAGNE DAEQPDGAKN 60
EASVSANASK QALLQAVSDA MASTRQMAKK FAFWSTQPVT KLDEQVTTNE CIEPNKEISE 120
IRALPYTLPG GFKWVTLDLN DANDLKELYT LLNENYVEDD DAMFRFDYQP EFLKWSLQPP 180
GWKRDWHVGV RVEKSGKLVG FISAIPSKLK SYDKVLKVVD INFLCVHKKL RSKRVAPVLI 240
REITRRVNLT GIFQAAYTAG VVLPTPVATC RYWHRSLNPK KLVDVRFSHL ARNMTMQRTM 300
KLYKLPDQPK TKGYRRITAK DMDKAHKLLE DYLKRFQLSP VFSKEEFRHW FTPKEGIIDC 360
FVVADEKGNI TDLTSYYCLP SSVMHHPVHK TVRAAYSFYN VSTKTPWLDL MNDALISARN 420
VQMDVYNALD LMENKKYFAP LKFGAGDGNL QYYLYNWRCP SMQPEEIALI LM 473
Keyword

KW-0012--Acyltransferase
KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR016181--Acyl_CoA_acyltransferase
IPR000903--MyristoylCoA_TrFase
IPR022677--MyristoylCoA_TrFase_C
IPR022678--MyristoylCoA_TrFase_CS
IPR022676--MyristoylCoA_TrFase_N

PROSITE

PS00975--NMT_1
PS00976--NMT_2

Pfam

PF01233--NMT
PF02799--NMT_C

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016020--C:membrane
GO:0004379--F:glycylpeptide N-tetradecanoyltransferase activity
GO:0007391--P:dorsal closure
GO:0018008--P:N-terminal peptidyl-glycine N-myristoylation
GO:0006499--P:N-terminal protein myristoylation
GO:0022008--P:neurogenesis