dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0002261
Uniprot Accession O61444; O61444_DROME; O61445;
Genbank Protein ID NP_001163551.1; NP_001262375.1; NP_477353.1;
Genbank Nucleotide ID NM_001170080.2; NM_001275446.1; NM_058005.5;
Protein Name MAP kinase kinase 4, isoform A
Protein Synonyms/Alias
Gene Name Mkk4
Gene Synonyms/Alias CG9738;Dmel_CG9738;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 13
PositionPeptidesSourceReferences ( PMIDs )
13KNLFATGSSRSRNPPPhosphoPep 2.019060867
14NLFATGSSRSRNPPDPHOSIDA;PhosphoPep 2.0;curated21081558; 19060867; 22817900
16FATGSSRSRNPPDQLPHOSIDA;PhosphoPep 2.0;curated21081558; 19060867; 22817900
24RNPPDQLSLNNLSIRPHOSIDA;PhosphoPep 2.0;curated21081558; 19060867; 22817900
29QLSLNNLSIRHPPSSPhosphoPep 2.0;curated19060867; 22817900
37IRHPPSSTSSTSSGSPhosphoPep 2.019060867
39HPPSSTSSTSSGSTSPhosphoPep 2.019060867
41PSSTSSTSSGSTSSGPhosphoPep 2.019060867
42SSTSSTSSGSTSSGSPhosphoPep 2.019060867
44TSSTSSGSTSSGSSSPhosphoPep 2.019060867
47TSSGSTSSGSSSSSQPhosphoPep 2.019060867
277ISGQLVDSIAKTKDAPhosphoPep 2.0;curated19060867; 22817900
424TANQQAES-------PHOSIDA;PhosphoPep 2.021081558; 19060867
Sequence
(Fasta)		MAERPKNLFA TGSSRSRNPP DQLSLNNLSI RHPPSSTSST SSGSTSSGSS SSSQHNHVTR 60
CFGAQQPQQT PPVASSQVPP VPAASSSSAA DRHRERIRQQ ACGKLQFGEG GANTHTFTSD 120
DLEDEGEIGR GAFGAVNKMT FKKLDKVMAV KRIRSTVDEK EQKQLLMDLE VVMKSNECIY 180
IVQFYGALFK EGDCWICMEL MDTSLDKFYK YIYEKQQRHI PESILAKITV ATVNALNYLK 240
EELKIIHRDV KPSNILLHRR GDIKLCDFGI SGQLVDSIAK TKDAGCRPYM APERIDPERA 300
KGYDVRSDVW SLGITLMEVA TGNFPYRKWD SVFEQLCQVV QGEPPRLLTS YNGMEFSKEF 360
VDFVNTCLIK KESDRPKYSR LLEMPFIRRG ETSHTDVAVY VADILESMEK DGITQFTANQ 420
QAES 425
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
Pfam

PF00069--Pkinase
Gene Ontology

GO:0030424--C:axon
GO:0005622--C:intracellular
GO:0005524--F:ATP binding
GO:0004708--F:MAP kinase kinase activity
GO:0004697--F:protein kinase C activity
GO:0004702--F:receptor signaling protein serine/threonine kinase activity
GO:0007257--P:activation of JUN kinase activity
GO:0007254--P:JNK cascade
GO:0048666--P:neuron development
GO:0048812--P:neuron projection morphogenesis
GO:0006468--P:protein phosphorylation
GO:0048082--P:regulation of adult chitin-containing cuticle pigmentation