dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0002255
Uniprot Accession O61305; DDX19_DROME;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name DEAD-box helicase Dbp80
Protein Synonyms/Alias
Gene Name Dbp80
Gene Synonyms/Alias Hel40;HEL80;CG17023;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)
ATP-dependent RNA helicase involved in mRNA export from the nucleus.
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
26KLNLDSKSGEETDFDdbPTM 3.0;UniProt17372656; 16381945; 23193290
30DSKSGEETDFDVADPdbPTM 3.0;Phospho.ELM 9.0;UniProt17372656; 18327897; 16381945; 23193290
Sequence
(Fasta)
MGDWAKKSED QEVSKLVDKL NLDSKSGEET DFDVADPAET SLLIKILGKG LVNTKLSLDL 60
QQKNPNSPLH SVKTFEALHL KASLLKGIYA MGFNTPSKIQ ETALPTLLAD PPQNMIAQSQ 120
SGTGKTAAFV LAMLSRVNVC LNHPQVLCLS PTYELAIQTG EVAARMGQFC REIKLRFAVR 180
GEEVDRSKKI EEHILIGTPG KLLDWGIKFR LFDMKKISVF VLDEADVMIA TQGHHDQCIR 240
IHKMLNPHCQ MLFFSATYGK EVMDFARLIV ADPTIIRLMR EEESLENIKQ YYVKCKNEEG 300
KYNAIQNIYG CISVGQAIIF CHTKRTAAWL AAKMTSDGHS VAVLTGDLTV VQRLDVLDRF 360
RSGLEKVLIT TNILSRGIDI EQLQVVVNFD LPVDLDGMAD CETYLHRIGR TGRFGKSGIA 420
INLITDEKTM KVCSDIEKHF NKKIEVLNTD SADDIEKIGT 461
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0347--Helicase
KW-0378--Hydrolase
KW-0472--Membrane
KW-0509--mRNA transport
KW-0906--Nuclear pore complex
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0694--RNA-binding
KW-0811--Translocation
KW-0813--Transport

Interpro

IPR011545--DEAD/DEAH_box_helicase_dom
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR014014--RNA_helicase_DEAD_Q_motif

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51195--Q_MOTIF

Pfam

PF00270--DEAD
PF00271--Helicase_C

Gene Ontology

GO:0005737--C:cytoplasm
GO:0031965--C:nuclear membrane
GO:0044614--C:nuclear pore cytoplasmic filaments
GO:0005524--F:ATP binding
GO:0004386--F:helicase activity
GO:0003723--F:RNA binding
GO:0051028--P:mRNA transport
GO:0015031--P:protein transport