dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0002050
Uniprot Accession O60234; GMFG_HUMAN; Q6IB37;
Genbank Protein ID NP_001287937.1; NP_004868.1;
Genbank Nucleotide ID NM_001301008.1; NM_004877.3;
Protein Name Glia maturation factor gamma
Protein Synonyms/Alias
Gene Name GMFG
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 6
PositionPeptidesSourceReferences ( PMIDs )
2------MSDSLVVCEdbPTM 3.0;PhosphoSitePlus16873721; 16381945; 23193290; 22135298
4----MSDSLVVCEVDdbPTM 3.0;PhosphoSitePlus16873721; 16381945; 23193290; 22135298
27KFRFRKETDNAAIIMPhosphoSitePlus;curated22135298; 23882029
83VHDDGRVSYPLCFIFPhosphoSitePlus22135298
84HDDGRVSYPLCFIFSPhospho.ELM 9.0;PhosphoPep 2.0;PhosphoSitePlus15592455; 19060867; 22135298
104KPEQQMMYAGSKNRLPhosphoSitePlus22135298
Sequence
(Fasta)
MSDSLVVCEV DPELTEKLRK FRFRKETDNA AIIMKVDKDR QMVVLEEEFQ NISPEELKME 60
LPERQPRFVV YSYKYVHDDG RVSYPLCFIF SSPVGCKPEQ QMMYAGSKNR LVQTAELTKV 120
FEIRTTDDLT EAWLQEKLSF FR 143
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0181--Complete proteome
KW-0339--Growth factor
KW-0621--Polymorphism
KW-1185--Reference proteome

Interpro

IPR002108--ADF-H
IPR029006--ADF-H/Gelsolin-like_dom
IPR011171--GMF
IPR030076--GMFG

PROSITE

PS51263--ADF_H

Pfam

PF00241--Cofilin_ADF

Gene Ontology

GO:0005622--C:intracellular
GO:0008047--F:enzyme activator activity
GO:0004860--F:protein kinase inhibitor activity
GO:0034316--P:negative regulation of Arp2/3 complex-mediated actin nucleation
GO:1904030--P:negative regulation of cyclin-dependent protein kinase activity
GO:0043085--P:positive regulation of catalytic activity
GO:0006468--P:protein phosphorylation
GO:2000249--P:regulation of actin cytoskeleton reorganization