dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0001943
Uniprot Accession O55156; CLIP2_RAT;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name CAP-Gly domain-containing linker protein 2
Protein Synonyms/Alias Cytoplasmic linker protein 115;CLIP-115;Cytoplasmic linker protein 2;
Gene Name Clip2
Gene Synonyms/Alias Cyln2;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)		 Seems to link microtubules to dendritic lamellar body (DLB), a membranous organelle predominantly present in bulbous dendritic appendages of neurons linked by dendrodendritic gap junctions. May operate in the control of brain-specific organelle translocations.
Phosphorylation Sites
 dbPAF PTMs: 10
PositionPeptidesSourceReferences ( PMIDs )
17PGRGGKHSSPVGRPScurated23984901
18GRGGKHSSPVGRPSIcurated25532521
203SVKTGNESGSNLSDSdbPTM 3.0;PhosphoSitePlus;UniProt;curated16641100; 16381945; 23193290; 22135298; 22673903; 22817900;
208NESGSNLSDSGSVKRdbPTM 3.0;PhosphoSitePlus;UniProt;curated16641100; 16381945; 23193290; 22135298; 22673903; 22817900;
210SGSNLSDSGSVKRGDdbPTM 3.0;PhosphoSitePlus;curated16641100; 16381945; 23193290; 22135298; 22817900
212SNLSDSGSVKRGDKDdbPTM 3.0;PhosphoSitePlus;curated16641100; 16381945; 23193290; 22135298; 22817900
294IRIGFPSTSPAKAKKcurated25532521
295RIGFPSTSPAKAKKTcurated23984901
923LLEANRHSPGPERDLPhosphoSitePlus;UniProt;curated22135298; 22673903; 25532521
973LSEQKRYSLIDPASAcurated23984901
Sequence
(Fasta)		MQKPSGLKPP GRGGKHSSPV GRPSIGSASS SVVASASGSK EGSPLHKQAS GPSSAGATTT 60
VSEKPGPKAA EVGDDFLGDF VVGERVWVNG VKPGVVQYLG ETQFAPGQWA GVVLDDPVGK 120
NDGAVGGLRY FECPALQGIF TRPSKLTRQP AAEGSGSDGH SVESLTAQNL SLHSGTATPP 180
LTGRVIPLRE SVLNSSVKTG NESGSNLSDS GSVKRGDKDL HLGDRVLVGG TKTGVVRYVG 240
ETDFAKGEWC GVELDEPLGK NDGAVAGTRY FQCPPKFGLF APIHKVIRIG FPSTSPAKAK 300
KTKRMAMGVS ALTHSPSSSS ISSVSSVASS VGGRPSRSGL LTETSSRYAR KISGTTALQE 360
ALKEKQQHIE QLLAERDLER AEVAKATSHI CEVEKEIALL KAQHEQYVAE AEEKLQRARL 420
LVENVRKEKV DLSNQLEEER RKVEDLQFRV EEESITKGDL ETQTQLEHAR IGELEQSLLL 480
EKAQAERLLR ELADNRLTTV AEKSRVLQLE EELSLRRGEI EELQHCLLQS GPPPADHPEA 540
AETLRLRERL LSASKEHQRD STLLQDKYEH MLKTYQTEVD KLRAANEKYA QEVADLKAKV 600
QQATTENMGL MDNWKSKLDS LASDHQKSLE DLKATLNSGP GAQQKEIGEL KALVEGIKME 660
HQLELGNLQA KHDLETAMHG KEKEGLRQKL QEAQEELAGL QQHWRAQLEE QAAAPAELQE 720
AQDQCRDAQL RVQELEGLDV EYRGQAQAIE FLKEQISLAE KKMLDYEMLQ RAEAQSRQEA 780
ERLREKLLVA ENRLQAVESL CSAQHSHVIE SNDLSEEKIR MKETVEGLQD KLNKRDKEVA 840
ALTSQMDMLR AQVSALENKC KSGEKKIDSL LKEKRRLEAE LEAVSRKTHD ASGQLVHISQ 900
ELLRKERSLN ELRVLLLEAN RHSPGPERDL SREVHKAEWR IKEQKLKDDI RGLREKLTGL 960
DKEKSLSEQK RYSLIDPASA PELLRLQHQL VSTEGCLRDA LDQAQQVERL VEALRGCSDR 1020
TQTISNSGSA NGIHQPDKAH KQEDKH 1047
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
Interpro

IPR000938--CAP-Gly_domain
IPR028394--CLIP2
PROSITE

PS00845--CAP_GLY_1
PS50245--CAP_GLY_2
Pfam

PF01302--CAP_GLY
Gene Ontology

GO:0005881--C:cytoplasmic microtubule
GO:0030425--C:dendrite
GO:1901588--C:dendritic microtubule
GO:0042599--C:lamellar body
GO:0008017--F:microtubule binding
GO:0051010--F:microtubule plus-end binding
GO:0007026--P:negative regulation of microtubule depolymerization