dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0001877
Uniprot Accession O54924; EXOC8_RAT;
Genbank Protein ID NP_620612.1;
Genbank Nucleotide ID NM_139043.1;
Protein Name Exocyst complex component 8
Protein Synonyms/Alias Exocyst complex 84 kDa subunit;
Gene Name Exoc8
Gene Synonyms/Alias Exo84;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Phosphorylation Sites
dbPAF PTMs: 4
PositionPeptidesSourceReferences ( PMIDs )
15RLRRQLESGGFEARLPhosphoSitePlus22135298
28RLYVKQLSQQSDGDRPhosphoSitePlus22135298
313EAEEELATPEAEEEKPhosphoSitePlus;UniProt22135298; 22673903
673RQNASFLYDTVLPVVPhosphoSitePlus22135298
Sequence
(Fasta)
MSDSGASRLR RQLESGGFEA RLYVKQLSQQ SDGDRDLQEH RQRVQALAEE TAQNLKRNVY 60
QNYRQFIETA REISYLESEM YQLSHLLTEQ KSSLESIPLA LLPAAAAGAS TGEDTAGAGP 120
RERGAAQAGF LPGPAGVPRE GPGTGEEGKQ RTLTTLLEKV EGCRDLLETP GQYLVYNGDL 180
VEYEADHMAQ LQRVHGFLMN DCLLVATWLP QRRGMYRYNA LYPLDRLAVV NVKDNPPMKD 240
MFKLLMFPES RIFQAENAKI KREWLEVLEE TKRALSDKRR REQEEAAALR APPPVTSKGS 300
NPFEDEAEEE LATPEAEEEK VDLSMEWIQE LPEDLDVCIA QRDFEGAVDL LDKLNHYLED 360
KPSPPSVKEL RAKVDERVRQ LTEVLVFELS PDRSLRGGPK ATRRAVSQLI RLGQCTKACE 420
LFLRNRAAAV HTAIRQLRIE GATLLYIHKL CHVFFTSLLE TAREFETDFA GTDSGCYSAF 480
VVWARSAMGM FVDAFSKQVF DSKESLSTAA ECVKVAKEHC QQLGEIGLDL TFIIHALLVK 540
DIQGALLSYK EIIIEATKHR NSEEMWRRMN LMTPEALGKL KEEMRSCGVS NFEQYTGDDC 600
WVNLSYTVVA FTKQTMGFLE EALKLYFPEL HMVLLESLVE VILVAVQHVD YSLRCEQDPE 660
KKTFIRQNAS FLYDTVLPVV ERRFEEGVGK PAKQLQDLRN ASRLLRVNPE STTSVV 717
Keyword

KW-0002--3D-structure
KW-0966--Cell projection
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0903--Direct protein sequencing
KW-0268--Exocytosis
KW-0597--Phosphoprotein
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport

Interpro

IPR016159--Cullin_repeat-like_dom
IPR032403--Exo84_C
IPR011993--PH/PTB_dom
IPR001849--PH_domain

PROSITE

PS50003--PH_DOMAIN

Pfam

PF16528--Exo84_C

Gene Ontology

GO:0000145--C:exocyst
GO:0030426--C:growth cone
GO:0005770--C:late endosome
GO:0016020--C:membrane
GO:0048471--C:perinuclear region of cytoplasm
GO:0034613--P:cellular protein localization
GO:0007032--P:endosome organization
GO:0001927--P:exocyst assembly
GO:0051601--P:exocyst localization
GO:0006887--P:exocytosis
GO:0022617--P:extracellular matrix disassembly
GO:0015031--P:protein transport