dbPAF Protein Information
| Tag | Content | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0001876 | ||||||||||||
| Uniprot Accession | O54923; EXOC6_RAT; | ||||||||||||
| Genbank Protein ID | NP_062150.2; | ||||||||||||
| Genbank Nucleotide ID | NM_019277.2; | ||||||||||||
| Protein Name | Exocyst complex component 6 | ||||||||||||
| Protein Synonyms/Alias | Exocyst complex component Sec15A;SEC15-like protein 1;rSec15; | ||||||||||||
| Gene Name | Exoc6 | ||||||||||||
| Gene Synonyms/Alias | Sec15;Sec15a;Sec15l1; | ||||||||||||
| Organism | Rattus norvegicus(Rat) | ||||||||||||
| NCBI Taxa ID | 10116 | ||||||||||||
| Functional Description (View all) |
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Together with RAB11A, RAB3IP, RAB8A, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. | ||||||||||||
| Phosphorylation Sites |
dbPAF PTMs: 2
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| Sequence (Fasta) | MAESGEALGT VPEHERILQE IESTDTACVG PTLRSVYDGQ PNAHKKFMEK LDACIRNHDK 60 EIEKMCNFHH QGFVDAITEL LKVRADAEKL KVQVTDTNRR FQDAGKEVIE QTEDIIRCRI 120 QQRNITTVVE KLQLCLPVLE MYSKLKEQMS MQRYYSALKT MEQLENVYFP RVSQYRFCQL 180 MMDTLPKLRE DIKDISMSDL KDFLESIRKH SDKIGETAMK QAQQQKSFSI AVQKQTNMRF 240 GKNMHVNNDR TLEEKSDIIL KHTLEEEAEN DEEVLTVQDL VDFSPVYRCS HIYSALGDEE 300 TFENYYRKQR KKQARLVLQP QSSVHETVDG YRRYFTQIVG FFVVEDHILH VTQGLVTRAY 360 TDELWNMALS KIIAVLRAHS SYCTDPDLVL ELKNLIVIFA DTLQGYGFSV NRLFDLLFEI 420 RDQYNETLLK KWAGIFRDIF EEDNYSPIPI GSEEEYKMVI SKFPFQDPDL EKQSFPKKFP 480 MSQSVPLIYI QVKEFIYASL KFSESLHRSS TEIDDMLRKS TNLLLTRILS SCLLNLIRKP 540 HIGLTELVQI IINTTHLEQA CKYLEDFITN ITNISQETVH TTRLYGLSTF KDARHAAEGE 600 IYTKLNQKID EFVQLADYDW TMAESDGRAS GYLMDLINFL RSIFQVFTHL PGKVAQTACM 660 SACQHLSTSL MQMLLDSELK QISMGAVQQF NLDVIQCELF ASSEPVPGFQ GDTLQLAFID 720 LRQLLDLFMV WDWSTYLADY GQPASKYLRV NPHAALTLLE KMKDTSKKNN IFAQFRKNDR 780 DRQKLIETVV KQLRGLVTGM SQHM 805 |
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| Keyword | KW-0181--Complete proteome |
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| Interpro | IPR007225--Sec15 |
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| PROSITE | |||||||||||||
| Pfam | PF04091--Sec15 |
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| Gene Ontology | GO:0000145--C:exocyst |