dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0001875
Uniprot Accession O54922; EXOC7_RAT;
Genbank Protein ID NP_073182.1; XP_006220984.1; XP_008766651.1;
Genbank Nucleotide ID NM_022691.1; XM_006220922.2; XM_008768429.1;
Protein Name Exocyst complex component 7
Protein Synonyms/Alias Exocyst complex component Exo70;rExo70;
Gene Name Exoc7
Gene Synonyms/Alias Exo70;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps directing the vesicle to the precise site of fusion (By similarity).
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
133FQDNSPDSPELNKVKPhosphoSitePlus;UniProt22135298; 22673903
250SSSGVPYSPAIPNKRdbPTM 3.0;PhosphoSitePlus;curated22595671; 16381945; 23193290; 22135298; 23984901
Sequence
(Fasta)
MIPPQEASAR RREIEDKLKQ EEETLSFIRD SLEKSDQLTK NMVSILSSFE SRLMKLENSI 60
IPVHKQTENL QRLQENVEKT LSCLDHVISY YHVASDTEKI IREGPTGRLE EYLGSMAKIQ 120
KAVEYFQDNS PDSPELNKVK LLFERGKESL ESEFRSLMTR HSKVISPVLV LDLISADDEL 180
EVQEDVVLEH LPESVLQDVI RISRWLVEYG RNQDFMNVYY QIRSSQLDRS IKGLKEHFRK 240
SSSSSGVPYS PAIPNKRKDT PTKKPIKRPG RDDMLDVETD AYIHCVSAFV RLAQSEYQLL 300
MGIIPEHHQK KTFDSLIQDA LDGLMLEGEN IVSAARKAII RHDFSTVLTV FPILRHLKQT 360
KPEFDQVLQG TAASTKNKLP GLITSMETIG AKALEDFADN IKNDPDKEYN MPKDGTVHEL 420
TSNAILFLQQ LLDFQETAGA MLASQETSSS ATSYNSEFSK RLLSTYICKV LGNLQLNLLS 480
KSKVYEDPAL SAIFLHNNYN YILKSLEKSE LIQLVAVTQK TAERSYREHI EQQIQTYQRS 540
WLKVTDYIAE KNLPVFQPGV KLRDKERQMI KERFKGFNDG LEELCKIQKA WAIPDTEQRD 600
KIRQAQKSIV KETYGAFLHR YSSVPFTKNP EKYIKYRVEQ VGDMIDRLFD TSA 654
Keyword

KW-1003--Cell membrane
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0268--Exocytosis
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport

Interpro

IPR016159--Cullin_repeat-like_dom
IPR004140--Exo70

PROSITE
Pfam

PF03081--Exo70

Gene Ontology

GO:0005829--C:cytosol
GO:0000145--C:exocyst
GO:0005886--C:plasma membrane
GO:0006887--P:exocytosis
GO:0015031--P:protein transport