| Tag |
Content |
| dbPAF ID |
dbPAF-0001838 |
| Uniprot Accession |
O54800; CADH8_RAT; O54801;
|
| Genbank Protein ID |
|
| Genbank Nucleotide ID |
|
| Protein Name |
Cadherin-8 |
| Protein Synonyms/Alias |
|
| Gene Name |
Cdh8 |
| Gene Synonyms/Alias |
|
| Organism |
Rattus norvegicus(Rat) |
| NCBI Taxa ID |
10116 |
Functional Description
(View all) |
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.Functional Description
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. |
Phosphorylation Sites
|
dbPAF PTMs: 1 | Position | Peptides | Source | References ( PMIDs ) |
|---|
| 795 | ELYSVGESDKET--- | PhosphoSitePlus | 22135298 |
|
Sequence
(Fasta) | MPERLAETLL DLWTPLIILW ITLPSFVYMA PMNQAHVLTT GSPLELSRQS EEMRILNRSK 60
RGWVWNQMFV LEEFSGPEPI LVGRLHTDLD PGSKKIKYIL SGDGAGTIFQ INDITGDIHA 120
IKRLDREEKA EYTLTAQAVD WETNKPLEPP SEFIIKVQDI NDNAPEFLNG PYHATVPEMS 180
ILGTSVTNVT ATDADDPVYG NSAKLVYSIL EGQPYFSIEP ETAIIKTALP NMDREAKEEY 240
LVVIQAKDMG GHSGGLSGTT TLTVTLTDVN DNPPKFAQSL YHFSVPEDVV LGTAIGRVKA 300
NDQDIGENAQ SSYDIIDGDG TALFEITSDA QAQDGVIRLR KPLDFETKKS YTLKVEAANI 360
HIDPRFSGRG PFKDTATVKI VVEDADEPPV FSSPTYLLEV HENAALNSVI GQVTARDPDI 420
TSSPIRFSID RHTDLERQFN INADDGKITL ATPLDRELSV WHNISIIATE IRNHSQISRV 480
PVAIKVLDVN DNAPEFASEY EAFLCENGKP GQVIQTVSAM DKDDPKNGHF FLYSLLPEMV 540
NNPNFTIKKN EDNSLSILAK HNGFNRQKQE VYLLPIVISD SGNPPLSSTS TLTIRVCGCS 600
NDGVVQSCNV EPYVLPIGLS MGALIAILAC IILLLVIVVL FVTLRRHKNE PLIIKDDEDV 660
RENIIRYDDE GGGEEDTEAF DIATLQNPDG INGFLPRKDI KPDLQFMPRQ GLAPVPNGVD 720
VDEFINVRLH EADNDPTAPP YDSIQIYGYE GRGSVAGSLS SLESTTSDSD QNFDYLSDWG 780
PRFKRLGELY SVGESDKET
Fasta Sequence
>O54800|Cdh8|Rattus norvegicus(Rat)
MPERLAETLLDLWTPLIILWITLPSFVYMAPMNQAHVLTTGSPLELSRQSEEMRILNRSKRGWVWNQMFVLEEFSGPEPILVGRLHTDLDPGSKKIKYILSGDGAGTIFQINDITGDIHAIKRLDREEKAEYTLTAQAVDWETNKPLEPPSEFIIKVQDINDNAPEFLNGPYHATVPEMSILGTSVTNVTATDADDPVYGNSAKLVYSILEGQPYFSIEPETAIIKTALPNMDREAKEEYLVVIQAKDMGGHSGGLSGTTTLTVTLTDVNDNPPKFAQSLYHFSVPEDVVLGTAIGRVKANDQDIGENAQSSYDIIDGDGTALFEITSDAQAQDGVIRLRKPLDFETKKSYTLKVEAANIHIDPRFSGRGPFKDTATVKIVVEDADEPPVFSSPTYLLEVHENAALNSVIGQVTARDPDITSSPIRFSIDRHTDLERQFNINADDGKITLATPLDRELSVWHNISIIATEIRNHSQISRVPVAIKVLDVNDNAPEFASEYEAFLCENGKPGQVIQTVSAMDKDDPKNGHFFLYSLLPEMVNNPNFTIKKNEDNSLSILAKHNGFNRQKQEVYLLPIVISDSGNPPLSSTSTLTIRVCGCSNDGVVQSCNVEPYVLPIGLSMGALIAILACIILLLVIVVLFVTLRRHKNEPLIIKDDEDVRENIIRYDDEGGGEEDTEAFDIATLQNPDGINGFLPRKDIKPDLQFMPRQGLAPVPNGVDVDEFINVRLHEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESTTSDSDQNFDYLSDWGPRFKRLGELYSVGESDKET
|
| Keyword |
KW-0025--Alternative splicing
KW-0106--Calcium
KW-0130--Cell adhesion
KW-1003--Cell membrane
KW-0165--Cleavage on pair of basic residues
KW-0181--Complete proteome
KW-0325--Glycoprotein
KW-0472--Membrane
KW-0479--Metal-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix
|
| Interpro |
IPR002126--Cadherin
IPR015919--Cadherin-like
IPR020894--Cadherin_CS
IPR000233--Cadherin_cytoplasmic-dom
IPR027397--Catenin_binding_dom
|
| PROSITE |
PS00232--CADHERIN_1
PS50268--CADHERIN_2
|
| Pfam |
PF00028--Cadherin
PF01049--Cadherin_C
|
| Gene Ontology |
GO:0005887--C:integral component of plasma membrane
GO:0005509--F:calcium ion binding
GO:0007156--P:homophilic cell adhesion via plasma membrane adhesion molecules
GO:0016337--P:single organismal cell-cell adhesion
GO:0007283--P:spermatogenesis
|
