dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0001827
Uniprot Accession O54772; SMRD2_RAT; O54771;
Genbank Protein ID NP_114189.1;
Genbank Nucleotide ID NM_031983.2;
Protein Name SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2
Protein Synonyms/Alias 60 kDa BRG-1/Brm-associated factor subunit B;BRG1-associated factor 60B;BAF60B;
Gene Name Smarcd2
Gene Synonyms/Alias Baf60b;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology).
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
203IYISNTFSPSKADGDPhosphoSitePlus;curated22135298; 23984901
217DNSGTAGTPGGTPAAPhosphoSitePlus;curated22135298; 22817900; 21630457; 23984901
Sequence
(Fasta)
MSGRGAGGFP LPPLSPGGGA VAAALGAPPP PAGPGMLPNP ALRGPGPSGG MGVPGAAAFR 60
PMGPAGPAAQ YQRPGMSPGS RMPMAGLQVG PPAGSPFGTA APLRPGMPPT MMDPFRKRLL 120
VPQAQPPMPA QRRGLKRRKM ADKVLPQRIR ELVPESQAYM DLLAFERKLD QTIARKRMEI 180
QEAIKKPLTQ KRKLRIYISN TFSPSKADGD NSGTAGTPGG TPAADKVASW ELRVEGKLLD 240
DPSKQKRKFS SFFKSLVIEL DKELYGPDNH LVEWHRMPTT QETDGFQVKR PGDLNVKCTL 300
LLMLDHQPPQ YKLDPRLARL LGVHTQTRAA IMQALWLYIK HNQLQDGHER EYINCNRYFR 360
QIFSCGRLRF SEIPMKLAGL LQHPDPIVIN HVISVDPNDQ KKTACYDIDV EVDDPLKAQM 420
SNFLASTTNQ QEIASLDVKI HETIESINQL KTQRDFMLSF STEPQDFIQE WLRSQRRDLK 480
IITDVIGNPE EERRAAFYHQ PWAQEAVGRH IFAKVQQRRQ ELEQVLGIRL T 532
Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0832--Ubl conjugation

Interpro

IPR030090--BAF60B
IPR003121--SWIB_MDM2_domain

PROSITE
Pfam

PF02201--SWIB

Gene Ontology

GO:0000790--C:nuclear chromatin
GO:0016514--C:SWI/SNF complex
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980--F:RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0043044--P:ATP-dependent chromatin remodeling
GO:0006337--P:nucleosome disassembly
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated