| Tag |
Content |
| dbPAF ID |
dbPAF-0001821 |
| Uniprot Accession |
O54715; VAS1_RAT;
|
| Genbank Protein ID |
NP_113973.1;
|
| Genbank Nucleotide ID |
NM_031785.1;
|
| Protein Name |
V-type proton ATPase subunit S1 |
| Protein Synonyms/Alias |
|
| Gene Name |
Atp6ap1 |
| Gene Synonyms/Alias |
Atp6ip1;Atp6s1; |
| Organism |
Rattus norvegicus(Rat) |
| NCBI Taxa ID |
10116 |
Functional Description
(View all) |
Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.Functional Description
Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. |
Phosphorylation Sites
|
dbPAF PTMs: 2 |
Sequence
(Fasta) | MMAATVVSRI RTGTRWAPVL WLLLSLVAVA AAVAAEQQVP LVLWSSDRDL WAPVADTHEG 60
HITSDMQLST YLDPALELGP RNVLLFLQDK LSIEDFTAYG GVFGNKQDSA FSNLENALDL 120
APSSLVLPAV DWYAISTLTT YLQEKLGASP LHVDLATLKE LKLNASLPAL LLIRLPYTAS 180
SGLMAPREVL TGNDEVIGQV LSTLESEDVP YTAALTAVRP SRVARDVAMV AGGLGRQLLQ 240
TQVASPAIHP PVSYNDTAPR ILFWAQNFSV AYKDEWKDLT SLTFGVENLN LTGSFWNDSF 300
AMLSLTYEPL FGATVTFKFI LASRFYPVSA RYWFTMERLE IHSNGSVAHF NVSQVTGPSI 360
YSFHCEYVSS LSKKGSLLVT NVPSLWQMTL HNFQIQAFNV TGEQFSYASD CAGFFSPGIW 420
MGLLTTLFML FIFTYGLHMI LSLKTMDRFD DRKGPTITLT QIV
464Fasta Sequence
>O54715|Atp6ap1|Rattus norvegicus(Rat)
MMAATVVSRIRTGTRWAPVLWLLLSLVAVAAAVAAEQQVPLVLWSSDRDLWAPVADTHEGHITSDMQLSTYLDPALELGPRNVLLFLQDKLSIEDFTAYGGVFGNKQDSAFSNLENALDLAPSSLVLPAVDWYAISTLTTYLQEKLGASPLHVDLATLKELKLNASLPALLLIRLPYTASSGLMAPREVLTGNDEVIGQVLSTLESEDVPYTAALTAVRPSRVARDVAMVAGGLGRQLLQTQVASPAIHPPVSYNDTAPRILFWAQNFSVAYKDEWKDLTSLTFGVENLNLTGSFWNDSFAMLSLTYEPLFGATVTFKFILASRFYPVSARYWFTMERLEIHSNGSVAHFNVSQVTGPSIYSFHCEYVSSLSKKGSLLVTNVPSLWQMTLHNFQIQAFNVTGEQFSYASDCAGFFSPGIWMGLLTTLFMLFIFTYGLHMILSLKTMDRFDDRKGPTITLTQIV
|
| Keyword |
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0325--Glycoprotein
KW-0375--Hydrogen ion transport
KW-0406--Ion transport
KW-0472--Membrane
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport
KW-0926--Vacuole
|
| Interpro |
IPR008388--ATPase_V1-cplx_s1su
|
| PROSITE |
|
| Pfam |
|
| Gene Ontology |
GO:0016021--C:integral component of membrane
GO:0033180--C:proton-transporting V-type ATPase, V1 domain
GO:0005774--C:vacuolar membrane
GO:0005524--F:ATP binding
GO:0046933--F:proton-transporting ATP synthase activity, rotational mechanism
GO:0046961--F:proton-transporting ATPase activity, rotational mechanism
GO:0017137--F:Rab GTPase binding
GO:0007568--P:aging
GO:0015991--P:ATP hydrolysis coupled proton transport
GO:0008219--P:cell death
GO:0051656--P:establishment of organelle localization
GO:0045851--P:pH reduction
GO:0045780--P:positive regulation of bone resorption
GO:0070374--P:positive regulation of ERK1 and ERK2 cascade
GO:0045921--P:positive regulation of exocytosis
GO:0045669--P:positive regulation of osteoblast differentiation
GO:2001206--P:positive regulation of osteoclast development
|
