dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0001816
Uniprot Accession O54697; NALDL_RAT;
Genbank Protein ID NP_113947.1;
Genbank Nucleotide ID NM_031759.1;
Protein Name N-acetylated-alpha-linked acidic dipeptidase-like protein
Protein Synonyms/Alias
Gene Name Naaladl1
Gene Synonyms/Alias Naaladl;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Has no NAAG hydrolyzing activity (By similarity). Exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC.
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
683AFPEERYYSHVLWAPPhosphoSitePlus22135298
705FPGLANAYARAQEINPhosphoSitePlus22135298
Sequence
(Fasta)
MHWAKILGVG IGAAALLGLG IILGHFAIPK ATEPLASSVS DSQDLDLAIL DSVMGQLDAS 60
RIRENLRELS KEPHVATSAR DEALVQLLLG RWKDSASGLD TAKTYEYTVL LSFPSTEQPN 120
SVEVVGPNGT VFHSFQPFEK NLTGEQAEPN VLQPYAAYAP PGTPKGPLVY ANRGSEDDFK 180
KLEAEGINLK GTIALTRYGS VGRGAKAINA ARHGVVGVLV YTDPGDINDG KSLPNETFPN 240
SWGLPPSGVE RGSYYEYFGD PLTPYLPAHP VSFRLDPHNI SGFPPIPTQP IGFEDAKNLL 300
CNLNGTSAPD SWQGALGCEY KLGPGFEPNG NFPAGSEVKV SVYNRLELRN SSNVLGIIQG 360
AVEPDRYVIY GNHRDSWVHG AVDPSSGTAV LLEISRVLGT LLKKGTWRPR RSIIFASWGA 420
EEFGLIGSTE FTEEFLSKLQ ERTVTYINVD ISVFSNATLR AQGTPPVQSV IFSATKEISA 480
PGSSGLSIYD NWIRYTNRSS PVYGLVPSMG TLGAGSDYAS FIHFLGITSM DLAYTYDRSK 540
TSARIYPTYH TAFDTFDYVE KFLDPGFSSH QAVARTAGSV LLRLSDSLFL PLNVSDYSET 600
LQSFLQAAQE NLGALLESHN ISLGPLVTAV EKFKAAAAAL NQHILTLQKS SPDPLQVRMV 660
NDQLMLLERA FLNPRAFPEE RYYSHVLWAP NTASVATFPG LANAYARAQE INSGAEAWAE 720
VERQLSIAVM ALEGAAATLQ PVTDL 746
Keyword

KW-0121--Carboxypeptidase
KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0224--Dipeptidase
KW-0903--Direct protein sequencing
KW-0325--Glycoprotein
KW-0378--Hydrolase
KW-0472--Membrane
KW-0479--Metal-binding
KW-0482--Metalloprotease
KW-0511--Multifunctional enzyme
KW-0645--Protease
KW-1185--Reference proteome
KW-0735--Signal-anchor
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc

Interpro

IPR003137--PA_domain
IPR007484--Peptidase_M28
IPR007365--TFR-like_dimer_dom

PROSITE
Pfam

PF02225--PA
PF04389--Peptidase_M28
PF04253--TFR_dimer

Gene Ontology

GO:0016324--C:apical plasma membrane
GO:0016021--C:integral component of membrane
GO:0004180--F:carboxypeptidase activity
GO:0016805--F:dipeptidase activity
GO:0046872--F:metal ion binding
GO:0008237--F:metallopeptidase activity