dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0001809
Uniprot Accession O46072; KZ_DROME;
Genbank Protein ID NP_001284815.1; NP_476591.1;
Genbank Nucleotide ID NM_001297886.1; NM_057243.4;
Protein Name Probable ATP-dependent RNA helicase kurz
Protein Synonyms/Alias
Gene Name kz
Gene Synonyms/Alias CG3228;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
529ETIDDAASTVEDPKEdbPTM 3.0;Phospho.ELM 9.0;PHOSIDA;UniProt;curated18327897; 16381945; 23193290; 21081558; 22817900
530TIDDAASTVEDPKELdbPTM 3.0;Phospho.ELM 9.0;PHOSIDA;UniProt;curated18327897; 16381945; 23193290; 21081558; 22817900
Sequence
(Fasta)
MGKKVHNAKA RQNPQTIVDN SAVKKIQIDV DAVAGGNQVG YDEANALVLP SEKRATKIKV 60
DKVQHVKILS KKQRKHLQAI VDKKKKKEGR AQLLGDLAAV QIPEEELQQY TSISQVQTVG 120
LKRLPTLDEY LAKKKERQAQ VLAEKSSASG LRVNAIKGSK RKLLVEEEEE LQAKRKNPNV 180
ISVEEDDEDS SSSDEDDEEA PAQSAPIAIP TPVSIAPPQI AVKPPIKKLK PEPNPPACIH 240
QTVYVPVHRT TEVQNARLRL PILAEEQQVM ETINENPIVI VAGETGSGKT TQLPQFLYEA 300
GYAQHKMIGV TEPRRVAAIA MSKRVAHEMN LPESEVSYLI RFEGNVTPAT RIKFMTDGVL 360
LKEIETDFLL SKYSVIILDE AHERSVYTDI LVGLLSRIVP LRHKRGQPLK LIIMSATLRV 420
SDFTENTRLF KIPPPLLKVE ARQFPVTIHF QKRTPDDYVA EAYRKTLKIH NKLPEGGILI 480
FVTGQQEVNQ LVRKLRRTFP YHHAPTKDVA KNGKVSEEEK EETIDDAAST VEDPKELEFD 540
MKRVIRNIRK SKKKFLAQMA LPKINLDDYK LPGDDTEADM HEQPDEDDEQ EGLEEDNDDE 600
LGLEDESGMG SGQRQPLWVL PLYSLLSSEK QNRIFLPVPD GCRLCVVSTN VAETSLTIPH 660
IKYVVDCGRQ KTRLYDKLTG VSAFVVTYTS KASADQRAGR AGRISAGHCY RLYSSAVYND 720
CFEDFSQPDI QKKPVEDLML QMRCMGIDRV VHFPFPSPPD QVQLQAAERR LIVLGALEVA 780
KTENTDLPPA VTRLGHVISR FPVAPRFGKM LALSHQQNLL PYTVCLVAAL SVQEVLIETG 840
VQRDEDVAPG ANRFHRKRQS WAASGNYQLL GDPMVLLRAV GAAEYAGSQG RLPEFCAANG 900
LRQKAMSEVR KLRVQLTNEI NLNVSDVELG VDPELKPPTD AQARFLRQIL LAGMGDRVAR 960
KVPLADIADK EERRRLKYAY NCADMEEPAF LHVSSVLRQK APEWVIYQEA YELQNGDSTK 1020
MFIRGITAIE PEWLLLYVPL LCNIREVRED PAPRFDKTSG KIFCHVDATF GKSGWELPLG 1080
EVEMPLSEKA CCYFGMFLLD GEVCSRLADF RSKLKSTPAS VIKSWSSMNN KVLRFKRALI 1140
TKQIHNRQAL IDQWNSDPHF LLEEYQNLLY DVALSELTPL WPPVDKKEPQ RQ 1193
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0347--Helicase
KW-0378--Hydrolase
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0694--RNA-binding

Interpro

IPR011545--DEAD/DEAH_box_helicase_dom
IPR002464--DNA/RNA_helicase_DEAH_CS
IPR011709--DUF1605
IPR007502--Helicase-assoc_dom
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase

PROSITE

PS00690--DEAH_ATP_HELICASE
PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER

Pfam

PF00270--DEAD
PF04408--HA2
PF00271--Helicase_C
PF07717--OB_NTP_bind

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005730--C:nucleolus
GO:0005524--F:ATP binding
GO:0004004--F:ATP-dependent RNA helicase activity
GO:0004386--F:helicase activity
GO:0044822--F:poly(A) RNA binding
GO:0022008--P:neurogenesis
GO:0006396--P:RNA processing