dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0001803
Uniprot Accession O46037; VINC_DROME;
Genbank Protein ID NP_001284813.1; NP_001284814.1; NP_476820.1;
Genbank Nucleotide ID NM_001297884.1; NM_001297885.1; NM_057472.3;
Protein Name Vinculin
Protein Synonyms/Alias
Gene Name Vinc
Gene Synonyms/Alias CG3299;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)
Involved in cell adhesion. May be involved in the attachment of the actin-based microfilaments to the plasma membrane (By similarity).
Phosphorylation Sites
dbPAF PTMs: 4
PositionPeptidesSourceReferences ( PMIDs )
571AGRIRMNYPGSKAADcurated22817900
574IRMNYPGSKAADEHLcurated22817900
774VRPPPPETDDEDEGVdbPTM 3.0;PHOSIDA;PhosphoPep 2.0;UniProt;curated17372656; 16381945; 23193290; 21081558; 19060867; 22817900
784EDEGVFRTMPHANQPPhosphoPep 2.0;curated19060867; 22817900
Sequence
(Fasta)
MPVFHTKTIE SILDPVAQQV SRLVILHEEA EDGNAMPDLS RPVQVVSAAV ANLVKVGRDT 60
INSSDDKILR QDMPSALHRV EGASQLLEEA SDMLRSDPYS GPARKKLIEG SRGILQGTSS 120
LLLCFDESEV RKIIQECKRV LDYLAVAEVI NTMEQLVQFL KDLSPCLSKV HREVGAREKE 180
LTHQVHSEIL VRCLEQVKTL APILICSMKV YIHIVEQQGR GAEEAAENRN YLAARMSDEL 240
QEIIRVLQLT TYDEDTSELD NLTVLKKLSN AISNKMEQAN EWLSNPYALR GGVGEKALRQ 300
VIDNATEISE RCLPQDSYPI RKLADEVTAM ANTLCELRQE GKGQSPQAES LVRGIRDRMG 360
ELKSLVHQAV LGVDKAGVQQ TAHTIQGRLE QAVKWLQHPE INDGGLGERA INLIVEEGRK 420
VAEGCPGHQK AEIQQLCDEV ERLKRQAAGS GPAAKQAAKQ LTQKLYELKA AIQNALVNRI 480
VQDFMDVSTP LKQFTEAVLQ PEGTPGREQN FNQKSNNLQA FSDRASKTSR MVAAGGACGN 540
KKIAEILLSS AAQVDSLTPQ LISAGRIRMN YPGSKAADEH LQNLKQQYAD TVLRMRTLCD 600
QATDPADFIK TSEEHMQVYA KLCEDAIHAR QPQKMVDNTS NIARLINRVL LVAKQEADNS 660
EDPVFTERLN AAANRLERSL PAMVGDAKLV ATNIADPAAA AAWKNSFQRL LGDVREVRDA 720
IAPPQPPPLP TSLPPPIPEL SALHLSNQNA ERAPPRPPLP REGLAPVRPP PPETDDEDEG 780
VFRTMPHANQ PILIAARGLH QEVRQWSSKD NEIIAAAKRM AILMARLSEL VLSDSRGSKR 840
ELIATAKKIA EASEDVTRLA KELARQCTDR RIRTNLLQVC ERIPTIGTQL KILSTVKATM 900
LGAQGSDEDR EATEMLVGNA QNLMQSVKET VRAAEGASIK IRSDQTSNRL QWVRRQPWYQ 960
Y 962
Keyword

KW-0009--Actin-binding
KW-0130--Cell adhesion
KW-0965--Cell junction
KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR006077--Vinculin/catenin
IPR000633--Vinculin_CS

PROSITE

PS00664--VINCULIN_2

Pfam

PF01044--Vinculin

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005737--C:cytoplasm
GO:0005925--C:focal adhesion
GO:0005886--C:plasma membrane
GO:0003779--F:actin binding
GO:0005198--F:structural molecule activity
GO:0007155--P:cell adhesion
GO:0007016--P:cytoskeletal anchoring at plasma membrane
GO:0048812--P:neuron projection morphogenesis
GO:0006909--P:phagocytosis