dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0001656
Uniprot Accession O43825; B3GT2_HUMAN; B2RAB1; Q9BZQ9;
Genbank Protein ID NP_003774.1;
Genbank Nucleotide ID NM_003783.3;
Protein Name Beta-1,3-galactosyltransferase 2
Protein Synonyms/Alias
Gene Name B3GALT2
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N-acetylglucosamine (beta-GlcNAc) residue. Can also utilize substrates with a terminal galactose residue, albeit with lower efficiency. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N-acetylglucosamine (alpha-GlcNAc) or alpha-N-acetylgalactosamine (alpha-GalNAc) residues.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
63KENPVTYTFRGFRSTPhosphoSitePlus22135298
Sequence
(Fasta)
MLQWRRRHCC FAKMTWNAKR SLFRTHLIGV LSLVFLFAMF LFFNHHDWLP GRAGFKENPV 60
TYTFRGFRST KSETNHSSLR NIWKETVPQT LRPQTATNSN NTDLSPQGVT GLENTLSANG 120
SIYNEKGTGH PNSYHFKYII NEPEKCQEKS PFLILLIAAE PGQIEARRAI RQTWGNESLA 180
PGIQITRIFL LGLSIKLNGY LQRAILEESR QYHDIIQQEY LDTYYNLTIK TLMGMNWVAT 240
YCPHIPYVMK TDSDMFVNTE YLINKLLKPD LPPRHNYFTG YLMRGYAPNR NKDSKWYMPP 300
DLYPSERYPV FCSGTGYVFS GDLAEKIFKV SLGIRRLHLE DVYVGICLAK LRIDPVPPPN 360
EFVFNHWRVS YSSCKYSHLI TSHQFQPSEL IKYWNHLQQN KHNACANAAK EKAGRYRHRK 420
LH 423
Keyword

KW-0181--Complete proteome
KW-0325--Glycoprotein
KW-0328--Glycosyltransferase
KW-0333--Golgi apparatus
KW-0464--Manganese
KW-0472--Membrane
KW-1185--Reference proteome
KW-0735--Signal-anchor
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR002659--Glyco_trans_31

PROSITE
Pfam

PF01762--Galactosyl_T

Gene Ontology

GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0008499--F:UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity
GO:0009312--P:oligosaccharide biosynthetic process
GO:0006486--P:protein glycosylation