| Tag |
Content |
| dbPAF ID |
dbPAF-0001652 |
| Uniprot Accession |
O43819; SCO2_HUMAN; Q3T1B5; Q9UK87;
|
| Genbank Protein ID |
NP_001162580.1; NP_001162581.1; NP_001162582.1; NP_005129.2;
|
| Genbank Nucleotide ID |
NM_001169109.1; NM_001169110.1; NM_001169111.1; NM_005138.2;
|
| Protein Name |
Protein SCO2 homolog, mitochondrial |
| Protein Synonyms/Alias |
|
| Gene Name |
SCO2 |
| Gene Synonyms/Alias |
|
| Organism |
Homo sapiens(Human) |
| NCBI Taxa ID |
9606 |
Functional Description
(View all) |
Acts as a copper chaperone, transporting copper to the Cu(A) site on the cytochrome c oxidase subunit II (COX2).Functional Description
Acts as a copper chaperone, transporting copper to the Cu(A) site on the cytochrome c oxidase subunit II (COX2). |
Phosphorylation Sites
|
dbPAF PTMs: 5 |
Sequence
(Fasta) | MLLLTRSPTA WHRLSQLKPR VLPGTLGGQA LHLRSWLLSR QGPAETGGQG QPQGPGLRTR 60
LLITGLFGAG LGGAWLALRA EKERLQQQKR TEALRQAAVG QGDFHLLDHR GRARCKADFR 120
GQWVLMYFGF THCPDICPDE LEKLVQVVRQ LEAEPGLPPV QPVFITVDPE RDDVEAMARY 180
VQDFHPRLLG LTGSTKQVAQ ASHSYRVYYN AGPKDEDQDY IVDHSIAIYL LNPDGLFTDY 240
YGRSRSAEQI SDSVRRHMAA FRSVLS
267Fasta Sequence
>O43819|SCO2|Homo sapiens(Human)
MLLLTRSPTAWHRLSQLKPRVLPGTLGGQALHLRSWLLSRQGPAETGGQGQPQGPGLRTRLLITGLFGAGLGGAWLALRAEKERLQQQKRTEALRQAAVGQGDFHLLDHRGRARCKADFRGQWVLMYFGFTHCPDICPDELEKLVQVVRQLEAEPGLPPVQPVFITVDPERDDVEAMARYVQDFHPRLLGLTGSTKQVAQASHSYRVYYNAGPKDEDQDYIVDHSIAIYLLNPDGLFTDYYGRSRSAEQISDSVRRHMAAFRSVLS
|
| Keyword |
KW-0002--3D-structure
KW-0122--Cardiomyopathy
KW-0143--Chaperone
KW-0181--Complete proteome
KW-0186--Copper
KW-0225--Disease mutation
KW-0479--Metal-binding
KW-0496--Mitochondrion
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0809--Transit peptide
|
| Interpro |
IPR003782--SCO1/SenC
IPR017276--Synth_of_cyt-c-oxidase_Sco1/2
IPR012336--Thioredoxin-like_fold
|
| PROSITE |
PS51352--THIOREDOXIN_2
|
| Pfam |
PF02630--SCO1-SenC
|
| Gene Ontology |
GO:0005743--C:mitochondrial inner membrane
GO:0005759--C:mitochondrial matrix
GO:0005739--C:mitochondrion
GO:0030016--C:myofibril
GO:0005654--C:nucleoplasm
GO:0005507--F:copper ion binding
GO:0006878--P:cellular copper ion homeostasis
GO:0006825--P:copper ion transport
GO:0001654--P:eye development
GO:0010467--P:gene expression
GO:0001701--P:in utero embryonic development
GO:0003012--P:muscle system process
GO:0055114--P:oxidation-reduction process
GO:0008535--P:respiratory chain complex IV assembly
GO:0022904--P:respiratory electron transport chain
GO:0014823--P:response to activity
GO:0006367--P:transcription initiation from RNA polymerase II promoter
|
