dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0001651
Uniprot Accession O43818; U3IP2_HUMAN; B2R996; Q8IZ30;
Genbank Protein ID NP_004695.1;
Genbank Nucleotide ID NM_004704.4;
Protein Name U3 small nucleolar RNA-interacting protein 2
Protein Synonyms/Alias RRP9 homolog;U3 small nucleolar ribonucleoprotein-associated 55 kDa protein;U3 snoRNP-associated 55 kDa protein;U3-55K;
Gene Name RRP9
Gene Synonyms/Alias RNU3IP2;U355K;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 Component of a nucleolar small nuclear ribonucleoprotein particle (snoRNP) thought to participate in the processing and modification of pre-ribosomal RNA.
Phosphorylation Sites
 dbPAF PTMs: 14
PositionPeptidesSourceReferences ( PMIDs )
2------MSATAAARKdbPTM 3.0;HPRD 9;PHOSIDA;PhosphoSitePlus;curated20068231; 16381945; 23193290; 18988627; 21081558; 22135298
15RKRGKPASGAGAGAGPhosphoSitePlus22135298
32KRRRKADSAGDRGKSPhosphoSitePlus22135298
39SAGDRGKSKGGGKMNPhosphoSitePlus22135298
50GKMNEEISSDSESESdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;UniProt;curated17081983; 18669648; 19413330; 19690332; 16381945; 23193290;
51KMNEEISSDSESESLdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;UniProt;curated17081983; 18669648; 19413330; 19690332; 16381945; 23193290;
53NEEISSDSESESLAPdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;UniProt;curated17081983; 18669648; 19413330; 19690332; 16381945; 23193290;
55EISSDSESESLAPRKdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;curated18669648; 16381945; 23193290; 19690332; 19651622; 20068231;
57SSDSESESLAPRKPEdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;UniProt;curated18669648; 19690332; 16381945; 23193290; 18988627; 19060867;
74EEEELEETAQEKKLRPhosphoSitePlus;curated22135298; 25627689; 23911959; 22817900
245TGHRDAVSGLAFRRGdbPTM 3.0;HPRD 9;PhosphoSitePlus;curated20068231; 16381945; 23193290; 18988627; 22135298; 22817900
306TAGGRDGTVRVWKIPcurated26074081
458RIKEARNSVCIIPLRcurated20873877
475PVPPAAGS-------dbPTM 3.0;HPRD 9;PhosphoPep 2.0;PhosphoSitePlus;curated19007248; 16381945; 23193290; 18988627; 19060867; 22135298;
Sequence
(Fasta)		MSATAAARKR GKPASGAGAG AGAGKRRRKA DSAGDRGKSK GGGKMNEEIS SDSESESLAP 60
RKPEEEEEEE LEETAQEKKL RLAKLYLEQL RQQEEEKAEA RAFEEDQVAG RLKEDVLEQR 120
GRLQKLVAKE IQAPASADIR VLRGHQLSIT CLVVTPDDSA IFSAAKDCSI IKWSVESGRK 180
LHVIPRAKKG AEGKPPGHSS HVLCMAISSD GKYLASGDRS KLILIWEAQS CQHLYTFTGH 240
RDAVSGLAFR RGTHQLYSTS HDRSVKVWNV AENSYVETLF GHQDAVAALD ALSRECCVTA 300
GGRDGTVRVW KIPEESQLVF YGHQGSIDCI HLINEEHMVS GADDGSVALW GLSKKRPLAL 360
QREAHGLRGE PGLEQPFWIS SVAALLNTDL VATGSHSSCV RLWQCGEGFR QLDLLCDIPL 420
VGFINSLKFS SSGDFLVAGV GQEHRLGRWW RIKEARNSVC IIPLRRVPVP PAAGS 476
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0687--Ribonucleoprotein
KW-0694--RNA-binding
KW-0698--rRNA processing
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
Gene Ontology

GO:0031428--C:box C/D snoRNP complex
GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0032040--C:small-subunit processome
GO:0044822--F:poly(A) RNA binding
GO:0006364--P:rRNA processing