dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0001650
Uniprot Accession O43815; STRN_HUMAN; Q3KP65; Q53TQ8; Q9NP38;
Genbank Protein ID NP_003153.2;
Genbank Nucleotide ID NM_003162.3;
Protein Name Striatin
Protein Synonyms/Alias
Gene Name STRN
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 Calmodulin-binding protein which may function as scaffolding or signaling protein and may play a role in dendritic Ca(2+) signaling.
Phosphorylation Sites
 dbPAF PTMs: 35 (View all)
PositionPeptidesSourceReferences ( PMIDs )
121AKYHKLKYGTELNQGcurated23090842
123YHKLKYGTELNQGDMcurated23090842
134QGDMKPPSYDSDEGNcurated25627689; 23898821; 23663014
135GDMKPPSYDSDEGNEPhosphoSitePlus;curated22135298; 23090842; 24961811
137MKPPSYDSDEGNETEdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoSitePlus;curated18669648; 16381945; 23193290; 18452278; 18988627; 22135298;
143DSDEGNETEVQPQQNdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoSitePlus;curated18669648; 16381945; 23193290; 18452278; 18988627; 22135298;
151EVQPQQNSQLMWKQGcurated23090842
172YLQEVGYTDTILDVKPhosphoSitePlus22135298
174QEVGYTDTILDVKSKPhosphoSitePlus22135298
191RALLGFSSDVTDREDcurated25849741
204EDDKNQDSVVNGTEAPhosphoSitePlus;curated22135298; 25627689
227AKSELTDSASVLDNFPhosphoSitePlus;curated22135298; 25627689; 23917254
229SELTDSASVLDNFKFPhosphoSitePlus;curated22135298; 25627689; 23917254; 20873877
239DNFKFLESAAADFSDcurated20873877
245ESAAADFSDEDEDDDdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;UniProt;curated18669648; 19369195; 19413330; 19690332; 16381945; 23193290;
259DVDGREKSVIDTSTIPhosphoSitePlus;curated22135298; 25850435; 25627689; 23917254
264EKSVIDTSTIVRKKAPhosphoPep 2.0;PhosphoSitePlus;curated19060867; 22135298; 25627689; 23917254
265KSVIDTSTIVRKKALPhosphoSitePlus;curated22135298; 25850435; 25627689
294EFDFLVTSEEGDNEScurated20873877
301SEEGDNESRSAGDGTcurated20873877
Sequence
(Fasta)		MDEQAGPGVF FSNNHPGAGG AKGLGPLAEA AAAGDGAAAA GAARAQYSLP GILHFLQHEW 60
ARFEVERAQW EVERAELQAQ IAFLQGERKG QENLKKDLVR RIKMLEYALK QERAKYHKLK 120
YGTELNQGDM KPPSYDSDEG NETEVQPQQN SQLMWKQGRQ LLRQYLQEVG YTDTILDVKS 180
KRVRALLGFS SDVTDREDDK NQDSVVNGTE AEVKETAMIA KSELTDSASV LDNFKFLESA 240
AADFSDEDED DDVDGREKSV IDTSTIVRKK ALPDSGEDRD TKEALKEFDF LVTSEEGDNE 300
SRSAGDGTDW EKEDQCLMPE AWNVDQGVIT KLKEQYKKER KGKKGVKRPN RSKLQDMLAN 360
LRDVDELPSL QPSVGSPSRP SSSRLPEHEI NRADEVEALT FPPSSGKSFI MGADEALESE 420
LGLGELAGLT VANEADSLTY DIANNKDALR KTWNPKFTLR SHFDGIRALA FHPIEPVLIT 480
ASEDHTLKMW NLQKTAPAKK STSLDVEPIY TFRAHKGPVL CVVMSSNGEQ CYSGGTDGLI 540
QGWNTTNPNI DPYDSYDPSV LRGPLLGHTD AVWGLAYSAA HQRLLSCSAD GTLRLWNTTE 600
VAPALSVFND TKELGIPASV DLVSSDPSHM VASFSKGYTS IFNMETQQRI LTLESNVDTT 660
ANSSCQINRV ISHPTLPISI TAHEDRHIKF YDNNTGKLIH SMVAHLEAVT SLAVDPNGLY 720
LMSGSHDCSI RLWNLESKTC IQEFTAHRKK FEESIHDVAF HPSKCYIASA GADALAKVFV 780
781
Keyword

KW-0007--Acetylation
KW-0025--Alternative splicing
KW-0112--Calmodulin-binding
KW-0966--Cell projection
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013258--Striatin_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF08232--Striatin
PF00400--WD40
Gene Ontology

GO:0005923--C:bicellular tight junction
GO:0005737--C:cytoplasm
GO:0043197--C:dendritic spine
GO:0016020--C:membrane
GO:0043025--C:neuronal cell body
GO:0014069--C:postsynaptic density
GO:0045211--C:postsynaptic membrane
GO:0070016--F:armadillo repeat domain binding
GO:0005516--F:calmodulin binding
GO:0030331--F:estrogen receptor binding
GO:0032403--F:protein complex binding
GO:0051721--F:protein phosphatase 2A binding
GO:0070830--P:bicellular tight junction assembly
GO:0016358--P:dendrite development
GO:0007626--P:locomotory behavior
GO:0008285--P:negative regulation of cell proliferation
GO:0016055--P:Wnt signaling pathway