dbPAF Protein Information
| Tag | Content |
|---|---|
| dbPAF ID | dbPAF-0001647 |
| Uniprot Accession | O43808; PM34_HUMAN; A8KA59; Q5TFL0; Q9UGW8; Q9UGY7; |
| Genbank Protein ID | NP_001269656.1; NP_006349.1; |
| Genbank Nucleotide ID | NM_001282727.1; NM_006358.3; |
| Protein Name | Peroxisomal membrane protein PMP34 |
| Protein Synonyms/Alias | 34 kDa peroxisomal membrane protein;Solute carrier family 25 member 17; |
| Gene Name | SLC25A17 |
| Gene Synonyms/Alias | PMP34; |
| Organism | Homo sapiens(Human) |
| NCBI Taxa ID | 9606 |
| Functional Description (View all) |
Peroxisomal transporter for multiple cofactors like coenzyme A (CoA), flavin adenine dinucleotide (FAD), flavin mononucleotide (FMN) and nucleotide adenosine monophosphate (AMP), and to a lesser extend for nicotinamide adenine dinucleotide (NAD(+)), adenosine diphosphate (ADP) and adenosine 3',5'-diphosphate (PAP). May catalyze the transport of free CoA, FAD and NAD(+) from the cytosol into the peroxisomal matrix by a counter-exchange mechanism. Inhibited by pyridoxal 5'-phosphate and bathophenanthroline in vitro. |
| Phosphorylation Sites |
dbPAF PTMs: 6 |
| Sequence (Fasta) | MASVLSYESL VHAVAGAVGS VTAMTVFFPL DTARLRLQVD EKRKSKTTHM VLLEIIKEEG 60 LLAPYRGWFP VISSLCCSNF VYFYTFNSLK ALWVKGQHST TGKDLVVGFV AGVVNVLLTT 120 PLWVVNTRLK LQGAKFRNED IVPTNYKGII DAFHQIIRDE GISALWNGTF PSLLLVFNPA 180 IQFMFYEGLK RQLLKKRMKL SSLDVFIIGA VAKAIATTVT YPLQTVQSIL RFGRHRLNPE 240 NRTLGSLRNI LYLLHQRVRR FGIMGLYKGL EAKLLQTVLT AALMFLVYEK LTAATFTVMG 300 LKRAHQH 308 |
| Keyword | KW-0181--Complete proteome |
| Interpro | IPR002067--Mit_carrier |
| PROSITE | PS50920--SOLCAR |
| Pfam | PF00153--Mito_carr |
| Gene Ontology | GO:0005779--C:integral component of peroxisomal membrane |