dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0001643
Uniprot Accession O43790; KRT86_HUMAN; P78387;
Genbank Protein ID NP_002275.1; XP_011536638.1; XP_011536639.1; XP_011536640.1;
Genbank Nucleotide ID NM_002284.3; XM_011538336.1; XM_011538337.1; XM_011538338.1;
Protein Name Keratin, type II cuticular Hb6
Protein Synonyms/Alias Hair keratin K2.11;Keratin-86;K86;Type II hair keratin Hb6;Type-II keratin Kb26;
Gene Name KRT86
Gene Synonyms/Alias KRTHB6;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 9
PositionPeptidesSourceReferences ( PMIDs )
47GLTGGFGSHSVCGGFdbPTM 3.0;HPRD 9;curated20068231; 16381945; 23193290; 18988627
49TGGFGSHSVCGGFRAdbPTM 3.0;HPRD 9;PhosphoSitePlus;curated20068231; 16381945; 23193290; 18988627; 22135298
203EEVSLRATAENEFVAdbPTM 3.0;HPRD 9;PhosphoSitePlus20068231; 16381945; 23193290; 18988627; 22135298
252EEIRVLQSHISDTSVPhosphoSitePlus22135298
258QSHISDTSVVVKLDNdbPTM 3.0;HPRD 9;PhosphoSitePlus;curated20068231; 16381945; 23193290; 18988627; 22135298
282IAEIKAQYDDIVTRSdbPTM 3.0;PhosphoSitePlus;curated21049007; 16381945; 23193290; 22135298; 22817900; 26267517
455VVSTRVSSVPSNSNVPhosphoSitePlus22135298
460VSSVPSNSNVVVGTTPhosphoSitePlus22135298
466NSNVVVGTTNACAPSPhosphoSitePlus22135298
Sequence
(Fasta)		MTCGSYCGGR AFSCISACGP RPGRCCITAA PYRGISCYRG LTGGFGSHSV CGGFRAGSCG 60
RSFGYRSGGV CGPSPPCITT VSVNESLLTP LNLEIDPNAQ CVKQEEKEQI KSLNSRFAAF 120
IDKVRFLEQQ NKLLETKLQF YQNRECCQSN LEPLFEGYIE TLRREAECVE ADSGRLASEL 180
NHVQEVLEGY KKKYEEEVSL RATAENEFVA LKKDVDCAYL RKSDLEANVE ALIQEIDFLR 240
RLYEEEIRVL QSHISDTSVV VKLDNSRDLN MDCIIAEIKA QYDDIVTRSR AEAESWYRSK 300
CEEMKATVIR HGETLRRTKE EINELNRMIQ RLTAEVENAK CQNSKLEAAV AQSEQQGEAA 360
LSDARCKLAE LEGALQKAKQ DMACLIREYQ EVMNSKLGLD IEIATYRRLL EGEEQRLCEG 420
VGSVNVCVSS SRGGVVCGDL CASTTAPVVS TRVSSVPSNS NVVVGTTNAC APSARVGVCG 480
GSCKRC 487
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0225--Disease mutation
KW-0403--Intermediate filament
KW-0416--Keratin
KW-1185--Reference proteome
Interpro

IPR001664--IF
IPR018039--Intermediate_filament_CS
IPR032444--Keratin_2_head
IPR003054--Keratin_II
PROSITE

PS00226--IF
Pfam

PF00038--Filament
PF16208--Keratin_2_head
Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005615--C:extracellular space
GO:0045095--C:keratin filament
GO:0005198--F:structural molecule activity