dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0001641
Uniprot Accession O43776; SYNC_HUMAN; B4DG16; Q53GU6;
Genbank Protein ID NP_004530.1;
Genbank Nucleotide ID NM_004539.3;
Protein Name Asparagine--tRNA ligase, cytoplasmic
Protein Synonyms/Alias Asparaginyl-tRNA synthetase;AsnRS;
Gene Name NARS
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 11
PositionPeptidesSourceReferences ( PMIDs )
14YVSDREGSDATGDGTPhosphoSitePlus;curated22135298; 25627689
61RWNVISKSQLKNIKKdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PHOSIDA;PhosphoSitePlus;UniProt;curated17924679; 16381945; 23193290; 18669648; 19276368; 20068231;
88EKKEAEDSLRREKNLdbPTM 3.0;PhosphoSitePlus;curated21406692; 16381945; 23193290; 22135298; 22817900
250SKILKARSMVTRCFRcurated22817900
253LKARSMVTRCFRDHFcurated22817900
393RPFKRMNYSDAIVWLdbPTM 3.0;HPRD 9;curated20068231; 16381945; 23193290; 18988627
394PFKRMNYSDAIVWLKdbPTM 3.0;HPRD 9;curated18452278; 16381945; 23193290; 18988627; 20068231
459CPEDSRLTESVDVLMdbPTM 3.0;HPRD 9;curated20068231; 16381945; 23193290; 18988627
482GSMRIFDSEEILAGYPhosphoPep 2.019060867
539HIRDVCLYPRFVQRCdbPTM 3.0;PhosphoSitePlus;curated18180459; 16381945; 23193290; 22135298; 22817900
547PRFVQRCTP------PhosphoSitePlus;curated22135298; 23090842
Sequence
(Fasta)		MVLAELYVSD REGSDATGDG TKEKPFKTGL KALMTVGKEP FPTIYVDSQK ENERWNVISK 60
SQLKNIKKMW HREQMKSESR EKKEAEDSLR REKNLEEAKK ITIKNDPSLP EPKCVKIGAL 120
EGYRGQRVKV FGWVHRLRRQ GKNLMFLVLR DGTGYLQCVL ADELCQCYNG VLLSTESSVA 180
VYGMLNLTPK GKQAPGGHEL SCDFWELIGL APAGGADNLI NEESDVDVQL NNRHMMIRGE 240
NMSKILKARS MVTRCFRDHF FDRGYYEVTP PTLVQTQVEG GATLFKLDYF GEEAFLTQSS 300
QLYLETCLPA LGDVFCIAQS YRAEQSRTRR HLAEYTHVEA ECPFLTFDDL LNRLEDLVCD 360
VVDRILKSPA GSIVHELNPN FQPPKRPFKR MNYSDAIVWL KEHDVKKEDG TFYEFGEDIP 420
EAPERLMTDT INEPILLCRF PVEIKSFYMQ RCPEDSRLTE SVDVLMPNVG EIVGGSMRIF 480
DSEEILAGYK REGIDPTPYY WYTDQRKYGT CPHGGYGLGL ERFLTWILNR YHIRDVCLYP 540
RFVQRCTP 549
Keyword

KW-0007--Acetylation
KW-0025--Alternative splicing
KW-0030--Aminoacyl-tRNA synthetase
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0903--Direct protein sequencing
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
Interpro

IPR004364--aa-tRNA-synt_II
IPR018150--aa-tRNA-synt_II-like
IPR006195--aa-tRNA-synth_II
IPR004522--Asn-tRNA-ligase
IPR002312--Asp/Asn-tRNA-synth_IIb
IPR012340--NA-bd_OB-fold
IPR004365--NA-bd_OB_tRNA
PROSITE

PS50862--AA_TRNA_LIGASE_II
Pfam

PF00152--tRNA-synt_2
PF01336--tRNA_anti-codon
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005739--C:mitochondrion
GO:0004816--F:asparagine-tRNA ligase activity
GO:0005524--F:ATP binding
GO:0003676--F:nucleic acid binding
GO:0006421--P:asparaginyl-tRNA aminoacylation
GO:0010467--P:gene expression
GO:0006418--P:tRNA aminoacylation for protein translation