dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0001640
Uniprot Accession O43772; MCAT_HUMAN; B2R7F4; Q9UIQ2;
Genbank Protein ID NP_000378.1;
Genbank Nucleotide ID NM_000387.5;
Protein Name Mitochondrial carnitine/acylcarnitine carrier protein
Protein Synonyms/Alias Carnitine/acylcarnitine translocase;CAC;Solute carrier family 25 member 20;
Gene Name SLC25A20
Gene Synonyms/Alias CAC;CACT;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 Mediates the transport of acylcarnitines of different length across the mitochondrial inner membrane from the cytosol to the mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway.
Phosphorylation Sites
 dbPAF PTMs: 7
PositionPeptidesSourceReferences ( PMIDs )
9ADQPKPISPLKNLLAdbPTM 3.0;PhosphoSitePlus;curated22115753; 16381945; 23193290; 22135298; 25850435; 25627689;
124GMLSGVFTTGIMTPGPhosphoSitePlus22135298
169EFGIRGIYKGTVLTLPhosphoSitePlus22135298
186DVPASGMYFMTYEWLPhosphoSitePlus22135298
190SGMYFMTYEWLKNIFPhosphoSitePlus22135298
198EWLKNIFTPEGKRVSPhosphoSitePlus22135298
205TPEGKRVSELSAPRIPhosphoSitePlus;curated22135298; 20833797
Sequence
(Fasta)		MADQPKPISP LKNLLAGGFG GVCLVFVGHP LDTVKVRLQT QPPSLPGQPP MYSGTFDCFR 60
KTLFREGITG LYRGMAAPII GVTPMFAVCF FGFGLGKKLQ QKHPEDVLSY PQLFAAGMLS 120
GVFTTGIMTP GERIKCLLQI QASSGESKYT GTLDCAKKLY QEFGIRGIYK GTVLTLMRDV 180
PASGMYFMTY EWLKNIFTPE GKRVSELSAP RILVAGGIAG IFNWAVAIPP DVLKSRFQTA 240
PPGKYPNGFR DVLRELIRDE GVTSLYKGFN AVMIRAFPAN AACFLGFEVA MKFLNWATPN 300
L 302
Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0225--Disease mutation
KW-0472--Membrane
KW-0496--Mitochondrion
KW-0999--Mitochondrion inner membrane
KW-1185--Reference proteome
KW-0677--Repeat
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport
Interpro

IPR018108--Mitochondrial_sb/sol_carrier
IPR023395--Mt_carrier_dom
PROSITE

PS50920--SOLCAR
Pfam

PF00153--Mito_carr
Gene Ontology

GO:0005737--C:cytoplasm
GO:0016021--C:integral component of membrane
GO:0005743--C:mitochondrial inner membrane
GO:0005739--C:mitochondrion
GO:0006853--P:carnitine shuttle
GO:0044255--P:cellular lipid metabolic process
GO:0044281--P:small molecule metabolic process