dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0001635
Uniprot Accession O43761; SNG3_HUMAN; B2R9S0;
Genbank Protein ID NP_004200.2;
Genbank Nucleotide ID NM_004209.5;
Protein Name Synaptogyrin-3
Protein Synonyms/Alias
Gene Name SYNGR3
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 Involved in the positive regulation of dopamine transporter activity. Probably facilitates the physical and functional interactions of the transporter with the dopamine vesicular storage system, allowing a more efficient loading of the vesicles with extracellular dopamine after release (By similarity).
Phosphorylation Sites
 dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
175LQRFRLGTDMSLFATPhosphoSitePlus22135298
182TDMSLFATEQLSTGAPhosphoSitePlus22135298
Sequence
(Fasta)		MEGASFGAGR AGAALDPVSF ARRPQTLLRV ASWVFSIAVF GPIVNEGYVN TDSGPELRCV 60
FNGNAGACRF GVALGLGAFL ACAAFLLLDV RFQQISSVRD RRRAVLLDLG FSGLWSFLWF 120
VGFCFLTNQW QRTAPGPATT QAGDAARAAI AFSFFSILSW VALTVKALQR FRLGTDMSLF 180
ATEQLSTGAS QAYPGYPVGS GVEGTETYQS PPFTETLDTS PKGYQVPAY
Keyword

KW-0007--Acetylation
KW-0965--Cell junction
KW-0181--Complete proteome
KW-0968--Cytoplasmic vesicle
KW-0472--Membrane
KW-1185--Reference proteome
KW-0770--Synapse
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR008253--Marvel
IPR016579--Synaptogyrin
PROSITE

PS51225--MARVEL
Pfam

PF01284--MARVEL
Gene Ontology

GO:0030054--C:cell junction
GO:0016021--C:integral component of membrane
GO:0031594--C:neuromuscular junction
GO:0008021--C:synaptic vesicle
GO:0030672--C:synaptic vesicle membrane
GO:0032411--P:positive regulation of transporter activity
GO:0021762--P:substantia nigra development