dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0001632
Uniprot Accession O43752; STX6_HUMAN; B2R652; B4DR17; Q5VY08; Q6FH83;
Genbank Protein ID NP_001273139.1; NP_005810.1;
Genbank Nucleotide ID NM_001286210.1; NM_005819.5;
Protein Name Syntaxin-6
Protein Synonyms/Alias
Gene Name STX6
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 Involved in intracellular vesicle trafficking.
Phosphorylation Sites
 dbPAF PTMs: 13
PositionPeptidesSourceReferences ( PMIDs )
2------MSMEDPFFVdbPTM 3.0;HPRD 9;PhosphoSitePlus;UniProt;curated18578522; 20068231; 21406692; 16381945; 23193290; 18988627;
83RKFNLDATELSIRKAdbPTM 3.0;PhosphoSitePlus;curated21406692; 16381945; 23193290; 22135298; 22817900
86NLDATELSIRKAFITdbPTM 3.0;PhosphoSitePlus;curated21406692; 16381945; 23193290; 22135298; 25627689; 22817900
107RDMKDQMSTSSVQALPhosphoSitePlus22135298
127RQALLGDSGSQNWSTdbPTM 3.0;HPRD 9;PHOSIDA;PhosphoSitePlus;curated20068231; 16381945; 23193290; 18988627; 21081558; 22135298;
129ALLGDSGSQNWSTGTdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;curated17525332; 16381945; 23193290; 20068231; 18988627; 21081558;
133DSGSQNWSTGTTDKYcurated25627689; 23663014
134SGSQNWSTGTTDKYGPhosphoSitePlus22135298
137QNWSTGTTDKYGRLDPhosphoSitePlus22135298
140STGTTDKYGRLDRELdbPTM 3.0;PhosphoSitePlus;curated18180459; 16381945; 23193290; 22135298; 22817900
152RELQRANSHFIEEQQdbPTM 3.0;PhosphoSitePlus;UniProt;curated19690332; 16381945; 23193290; 22135298; 22817900; 26074081
229LAKVSHMTSDRRQWCPhosphoSitePlus22135298
230AKVSHMTSDRRQWCAPhosphoSitePlus22135298
Sequence
(Fasta)		MSMEDPFFVV KGEVQKAVNT AQGLFQRWTE LLQDPSTATR EEIDWTTNEL RNNLRSIEWD 60
LEDLDETISI VEANPRKFNL DATELSIRKA FITSTRQVVR DMKDQMSTSS VQALAERKNR 120
QALLGDSGSQ NWSTGTTDKY GRLDRELQRA NSHFIEEQQA QQQLIVEQQD EQLELVSGSI 180
GVLKNMSQRI GGELEEQAVM LEDFSHELES TQSRLDNVMK KLAKVSHMTS DRRQWCAIAI 240
LFAVLLVVLI LFLVL 256
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0025--Alternative splicing
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport
Interpro

IPR015260--Syntaxin-6_N
IPR006012--Syntaxin/epimorphin_CS
IPR010989--t-SNARE
IPR000727--T_SNARE_dom
PROSITE

PS00914--SYNTAXIN
PS50192--T_SNARE
Pfam

PF05739--SNARE
PF09177--Syntaxin-6_N
Gene Ontology

GO:0030136--C:clathrin-coated vesicle
GO:0005769--C:early endosome
GO:0005794--C:Golgi apparatus
GO:0016021--C:integral component of membrane
GO:0048471--C:perinuclear region of cytoplasm
GO:0045335--C:phagocytic vesicle
GO:0005886--C:plasma membrane
GO:0031201--C:SNARE complex
GO:0043195--C:terminal bouton
GO:0005802--C:trans-Golgi network
GO:0032588--C:trans-Golgi network membrane
GO:0005484--F:SNAP receptor activity
GO:0019905--F:syntaxin binding
GO:0007032--P:endosome organization
GO:0090161--P:Golgi ribbon formation
GO:0048193--P:Golgi vesicle transport
GO:0006886--P:intracellular protein transport
GO:1903827--P:regulation of cellular protein localization
GO:0032880--P:regulation of protein localization
GO:0042147--P:retrograde transport, endosome to Golgi
GO:0006906--P:vesicle fusion