| Tag |
Content |
| dbPAF ID |
dbPAF-0001625 |
| Uniprot Accession |
O43734; CIKS_HUMAN; B2RAY9; E1P555; Q5R3A3; Q7Z6Q1; Q7Z6Q2; Q7Z6Q3; Q9H5W2; Q9H6Y3; Q9NS14; Q9UG72;
|
| Genbank Protein ID |
NP_001157753.1; NP_001157755.1; NP_671733.2; NP_679211.2; XP_006715382.1; XP_011533688.1;
|
| Genbank Nucleotide ID |
NM_001164281.2; NM_001164283.2; NM_147200.2; NM_147686.3; XM_006715319.2; XM_011535386.1;
|
| Protein Name |
Adapter protein CIKS |
| Protein Synonyms/Alias |
Connection to IKK and SAPK/JNK;Nuclear factor NF-kappa-B activator 1;ACT1;TRAF3-interacting protein 2; |
| Gene Name |
TRAF3IP2 |
| Gene Synonyms/Alias |
C6orf2;C6orf4;C6orf5;C6orf6; |
| Organism |
Homo sapiens(Human) |
| NCBI Taxa ID |
9606 |
Functional Description
(View all) |
Could be involved in the activation of both NF-kappa-B via a NF-kappa-B inhibitor kinase (IKK)-dependent mechanism and stress-activated protein kinase (SAPK)/JNK.Functional Description
Could be involved in the activation of both NF-kappa-B via a NF-kappa-B inhibitor kinase (IKK)-dependent mechanism and stress-activated protein kinase (SAPK)/JNK. |
Phosphorylation Sites
|
dbPAF PTMs: 6 |
Sequence
(Fasta) | MPPQLQETRM NRSIPVEVDE SEPYPSQLLK PIPEYSPEEE SEPPAPNIRN MAPNSLSAPT 60
MLHNSSGDFS QAHSTLKLAN HQRPVSRQVT CLRTQVLEDS EDSFCRRHPG LGKAFPSGCS 120
AVSEPASESV VGALPAEHQF SFMEKRNQWL VSQLSAASPD TGHDSDKSDQ SLPNASADSL 180
GGSQEMVQRP QPHRNRAGLD LPTIDTGYDS QPQDVLGIRQ LERPLPLTSV CYPQDLPRPL 240
RSREFPQFEP QRYPACAQML PPNLSPHAPW NYHYHCPGSP DHQVPYGHDY PRAAYQQVIQ 300
PALPGQPLPG ASVRGLHPVQ KVILNYPSPW DHEERPAQRD CSFPGLPRHQ DQPHHQPPNR 360
AGAPGESLEC PAELRPQVPQ PPSPAAVPRP PSNPPARGTL KTSNLPEELR KVFITYSMDT 420
AMEVVKFVNF LLVNGFQTAI DIFEDRIRGI DIIKWMERYL RDKTVMIIVA ISPKYKQDVE 480
GAESQLDEDE HGLHTKYIHR MMQIEFIKQG SMNFRFIPVL FPNAKKEHVP TWLQNTHVYS 540
WPKNKKNILL RLLREEEYVA PPRGPLPTLQ VVPL
575Fasta Sequence
>O43734|TRAF3IP2|Homo sapiens(Human)
MPPQLQETRMNRSIPVEVDESEPYPSQLLKPIPEYSPEEESEPPAPNIRNMAPNSLSAPTMLHNSSGDFSQAHSTLKLANHQRPVSRQVTCLRTQVLEDSEDSFCRRHPGLGKAFPSGCSAVSEPASESVVGALPAEHQFSFMEKRNQWLVSQLSAASPDTGHDSDKSDQSLPNASADSLGGSQEMVQRPQPHRNRAGLDLPTIDTGYDSQPQDVLGIRQLERPLPLTSVCYPQDLPRPLRSREFPQFEPQRYPACAQMLPPNLSPHAPWNYHYHCPGSPDHQVPYGHDYPRAAYQQVIQPALPGQPLPGASVRGLHPVQKVILNYPSPWDHEERPAQRDCSFPGLPRHQDQPHHQPPNRAGAPGESLECPAELRPQVPQPPSPAAVPRPPSNPPARGTLKTSNLPEELRKVFITYSMDTAMEVVKFVNFLLVNGFQTAIDIFEDRIRGIDIIKWMERYLRDKTVMIIVAISPKYKQDVEGAESQLDEDEHGLHTKYIHRMMQIEFIKQGSMNFRFIPVLFPNAKKEHVPTWLQNTHVYSWPKNKKNILLRLLREEEYVAPPRGPLPTLQVVPL
|
| Keyword |
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0225--Disease mutation
KW-0621--Polymorphism
KW-1185--Reference proteome
|
| Interpro |
IPR013568--SEFIR_dom
|
| PROSITE |
PS51534--SEFIR
|
| Pfam |
PF08357--SEFIR
|
| Gene Ontology |
GO:0005622--C:intracellular
GO:0001783--P:B cell apoptotic process
GO:0006959--P:humoral immune response
GO:0048305--P:immunoglobulin secretion
GO:0035556--P:intracellular signal transduction
GO:0002230--P:positive regulation of defense response to virus by host
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
|
