dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0001621
Uniprot Accession O43711; TLX3_HUMAN; Q96AD3;
Genbank Protein ID NP_066305.2;
Genbank Nucleotide ID NM_021025.2;
Protein Name T-cell leukemia homeobox protein 3
Protein Synonyms/Alias Homeobox protein Hox-11L2;
Gene Name TLX3
Gene Synonyms/Alias HOX11L2;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 5
PositionPeptidesSourceReferences ( PMIDs )
76PFEDAGSYSVNLSLAPhosphoSitePlus22135298
190KRFHRQKYLASAERAPhosphoSitePlus22135298
193HRQKYLASAERAALAPhosphoSitePlus22135298
202ERAALAKSLKMTDAQPhosphoSitePlus22135298
212MTDAQVKTWFQNRRTPhosphoSitePlus;curated22135298; 22817900
Sequence
(Fasta)
MEAPASAQTP HPHEPISFGI DQILNSPDQD SAPAPRGPDG ASYLGGPPGG RPGATYPSLP 60
ASFAGLGAPF EDAGSYSVNL SLAPAGVIRV PAHRPLPGAV PPPLPSALPA MPSVPTVSSL 120
GGLNFPWMES SRRFVKDRFT AAAALTPFTV TRRIGHPYQN RTPPKRKKPR TSFSRVQICE 180
LEKRFHRQKY LASAERAALA KSLKMTDAQV KTWFQNRRTK WRRQTAEERE AERQQASRLM 240
LQLQHDAFQK SLNDSIQPDP LCLHNSSLFA LQNLQPWEED SSKVPAVTSL V 292
Keyword

KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0238--DNA-binding
KW-0371--Homeobox
KW-0539--Nucleus
KW-1185--Reference proteome

Interpro

IPR017970--Homeobox_CS
IPR001356--Homeobox_dom
IPR020479--Homeobox_metazoa
IPR009057--Homeodomain-like

PROSITE

PS00027--HOMEOBOX_1
PS50071--HOMEOBOX_2

Pfam

PF00046--Homeobox

Gene Ontology

GO:0005634--C:nucleus
GO:0043565--F:sequence-specific DNA binding
GO:0007417--P:central nervous system development
GO:0045665--P:negative regulation of neuron differentiation
GO:0048665--P:neuron fate specification
GO:0001764--P:neuron migration
GO:0002087--P:regulation of respiratory gaseous exchange by neurological system process
GO:0006355--P:regulation of transcription, DNA-templated
GO:0007585--P:respiratory gaseous exchange