dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0001607
Uniprot Accession O43678; NDUA2_HUMAN; D6RJD6; Q6IAY8;
Genbank Protein ID NP_001171941.1; NP_002479.1;
Genbank Nucleotide ID NM_001185012.1; NM_002488.4;
Protein Name NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2
Protein Synonyms/Alias Complex I-B8;CI-B8;NADH-ubiquinone oxidoreductase B8 subunit;
Gene Name NDUFA2
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Phosphorylation Sites
 dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
7-MAAAAASRGVGAKLdbPTM 3.0;HPRD 9;PhosphoSitePlus;curated20068231; 16381945; 23193290; 18988627; 22135298; 22817900
Sequence
(Fasta)		MAAAAASRGV GAKLGLREIR IHLCQRSPGS QGVRDFIEKR YVELKKANPD LPILIRECSD 60
VQPKLWARYA FGQETNVPLN NFSADQVTRA LENVLSGKA
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-1015--Disulfide bond
KW-0249--Electron transport
KW-0472--Membrane
KW-0496--Mitochondrion
KW-0999--Mitochondrion inner membrane
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0679--Respiratory chain
KW-0813--Transport
Interpro

IPR016464--NADH_Ub_cplx-1_asu_su-2
IPR007741--Ribosome/NADH_DH
IPR012336--Thioredoxin-like_fold
PROSITE
Pfam

PF05047--L51_S25_CI-B8
Gene Ontology

GO:0005743--C:mitochondrial inner membrane
GO:0031966--C:mitochondrial membrane
GO:0005747--C:mitochondrial respiratory chain complex I
GO:0008137--F:NADH dehydrogenase (ubiquinone) activity
GO:0044237--P:cellular metabolic process
GO:0006120--P:mitochondrial electron transport, NADH to ubiquinone
GO:0022904--P:respiratory electron transport chain
GO:0044281--P:small molecule metabolic process