dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0001606
Uniprot Accession O43676; NDUB3_HUMAN; Q6IB80;
Genbank Protein ID NP_001244031.1; NP_002482.1; XP_011509532.1;
Genbank Nucleotide ID NM_001257102.1; NM_002491.2; XM_011511230.1;
Protein Name NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3
Protein Synonyms/Alias Complex I-B12;CI-B12;NADH-ubiquinone oxidoreductase B12 subunit;
Gene Name NDUFB3
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
60YMGGFAKSVSFSDVFPhosphoSitePlus22135298
Sequence
(Fasta)
MAHEHGHEHG HHKMELPDYR QWKIEGTPLE TIQKKLAAKG LRDPWGRNEA WRYMGGFAKS 60
VSFSDVFFKG FKWGFAAFVV AVGAEYYLES LNKDKKHH 99
Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0249--Electron transport
KW-0472--Membrane
KW-0488--Methylation
KW-0496--Mitochondrion
KW-0999--Mitochondrion inner membrane
KW-1185--Reference proteome
KW-0679--Respiratory chain
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport

Interpro

IPR012576--NDUFB3

PROSITE
Pfam

PF08122--NDUF_B12

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0016021--C:integral component of membrane
GO:0005743--C:mitochondrial inner membrane
GO:0005747--C:mitochondrial respiratory chain complex I
GO:0008137--F:NADH dehydrogenase (ubiquinone) activity
GO:0044237--P:cellular metabolic process
GO:0006120--P:mitochondrial electron transport, NADH to ubiquinone
GO:0022904--P:respiratory electron transport chain
GO:0044281--P:small molecule metabolic process