dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0001605
Uniprot Accession O43674; NDUB5_HUMAN; Q561V6;
Genbank Protein ID NP_001186886.1; NP_001186887.1; NP_002483.1;
Genbank Nucleotide ID NM_001199957.1; NM_001199958.1; NM_002492.3;
Protein Name NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial
Protein Synonyms/Alias Complex I-SGDH;CI-SGDH;NADH-ubiquinone oxidoreductase SGDH subunit;
Gene Name NDUFB5
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
182DKELIDHSPKATPDNPhosphoSitePlus;curated22135298; 25627689
Sequence
(Fasta)
MAAMSLLRRV SVTAVAALSG RPLGTRLGFG GFLTRGFPKA AAPVRHSGDH GKRLFVIRPS 60
RFYDRRFLKL LRFYIALTGI PVAIFITLVN VFIGQAELAE IPEGYVPEHW EYYKHPISRW 120
IARNFYDSPE KIYERTMAVL QIEAEKAELR VKELEVRKLM HVRGDGPWYY YETIDKELID 180
HSPKATPDN
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0249--Electron transport
KW-0472--Membrane
KW-0496--Mitochondrion
KW-0999--Mitochondrion inner membrane
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0679--Respiratory chain
KW-0809--Transit peptide
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport

Interpro

IPR019173--NADH_UbQ_OxRdtase_B5_su

PROSITE
Pfam

PF09781--NDUF_B5

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005743--C:mitochondrial inner membrane
GO:0005747--C:mitochondrial respiratory chain complex I
GO:0005739--C:mitochondrion
GO:0005654--C:nucleoplasm
GO:0008137--F:NADH dehydrogenase (ubiquinone) activity
GO:0044237--P:cellular metabolic process
GO:0006120--P:mitochondrial electron transport, NADH to ubiquinone
GO:0022904--P:respiratory electron transport chain
GO:0044281--P:small molecule metabolic process