| Tag |
Content |
| dbPAF ID |
dbPAF-0001598 |
| Uniprot Accession |
O43638; FOXS1_HUMAN; Q96D28;
|
| Genbank Protein ID |
NP_004109.1;
|
| Genbank Nucleotide ID |
NM_004118.3;
|
| Protein Name |
Forkhead box protein S1 |
| Protein Synonyms/Alias |
Forkhead-like 18 protein;Forkhead-related transcription factor 10;FREAC-10; |
| Gene Name |
FOXS1 |
| Gene Synonyms/Alias |
FKHL18;FREAC10; |
| Organism |
Homo sapiens(Human) |
| NCBI Taxa ID |
9606 |
Functional Description
(View all) |
Transcriptional repressor that suppresses transcription from the FASLG, FOXO3 and FOXO4 promoters. May have a role in the organization of the testicular vasculature (By similarity).Functional Description
Transcriptional repressor that suppresses transcription from the FASLG, FOXO3 and FOXO4 promoters. May have a role in the organization of the testicular vasculature (By similarity). |
Phosphorylation Sites
|
dbPAF PTMs: 1 | Position | Peptides | Source | References ( PMIDs ) |
|---|
| 55 | IMGRFAFYRHNRPGW | PhosphoSitePlus | 22135298 |
|
Sequence
(Fasta) | MQQQPLPGPG APTTEPTKPP YSYIALIAMA IQSSPGQRAT LSGIYRYIMG RFAFYRHNRP 60
GWQNSIRHNL SLNECFVKVP RDDRKPGKGS YWTLDPDCHD MFEHGSFLRR RRRFTRQTGA 120
EGTRGPAKAR RGPLRATSQD PGVPNATTGR QCSFPPELPD PKGLSFGGLV GAMPASMCPA 180
TTDGRPRPPM EPKEISTPKP ACPGELPVAT SSSSCPAFGF PAGFSEAESF NKAPTPVLSP 240
ESGIGSSYQC RLQALNFCMG ADPGLEHLLA SAAPSPAPPT PPGSLRAPLP LPTDHKEPWV 300
AGGFPVQGGS GYPLGLTPCL YRTPGMFFFE
331Fasta Sequence
>O43638|FOXS1|Homo sapiens(Human)
MQQQPLPGPGAPTTEPTKPPYSYIALIAMAIQSSPGQRATLSGIYRYIMGRFAFYRHNRPGWQNSIRHNLSLNECFVKVPRDDRKPGKGSYWTLDPDCHDMFEHGSFLRRRRRFTRQTGAEGTRGPAKARRGPLRATSQDPGVPNATTGRQCSFPPELPDPKGLSFGGLVGAMPASMCPATTDGRPRPPMEPKEISTPKPACPGELPVATSSSSCPAFGFPAGFSEAESFNKAPTPVLSPESGIGSSYQCRLQALNFCMGADPGLEHLLASAAPSPAPPTPPGSLRAPLPLPTDHKEPWVAGGFPVQGGSGYPLGLTPCLYRTPGMFFFE
|
| Keyword |
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0539--Nucleus
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
|
| Interpro |
IPR001766--Fork_head_dom
IPR018122--TF_fork_head_CS_1
IPR011991--WHTH_DNA-bd_dom
|
| PROSITE |
PS00657--FORK_HEAD_1
PS00658--FORK_HEAD_2
PS50039--FORK_HEAD_3
|
| Pfam |
PF00250--Forkhead
|
| Gene Ontology |
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0000981--F:RNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0043565--F:sequence-specific DNA binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0009653--P:anatomical structure morphogenesis
GO:0001568--P:blood vessel development
GO:0030154--P:cell differentiation
GO:0043433--P:negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0050885--P:neuromuscular process controlling balance
GO:0040018--P:positive regulation of multicellular organism growth
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0006351--P:transcription, DNA-templated
|
