dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0001579
Uniprot Accession O43567; RNF13_HUMAN; A6NC87; B3KR12; Q05D66; Q6IBJ9;
Genbank Protein ID NP_009213.1; NP_899237.1; XP_005247149.1; XP_011510674.1; XP_011510675.1; XP_011510676.1; XP_011510677.1; XP_011510678.1;
Genbank Nucleotide ID NM_007282.4; NM_183381.2; XM_005247092.2; XM_011512372.1; XM_011512373.1; XM_011512374.1; XM_011512375.1; XM_011512376.1;
Protein Name E3 ubiquitin-protein ligase RNF13
Protein Synonyms/Alias RING finger protein 13;
Gene Name RNF13
Gene Synonyms/Alias RZF;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
E3 ubiquitin-protein ligase that may play a role in controlling cell proliferation.
Phosphorylation Sites
dbPAF PTMs: 4
PositionPeptidesSourceReferences ( PMIDs )
247CAICLDEYEDGDKLRPhosphoSitePlus22135298
309ENEVTEHTPLLRPLAPhosphoSitePlus22135298
319LRPLASVSAQSFGALPhosphoSitePlus22135298
380RDYNIANTV------curated23663014
Sequence
(Fasta)
MLLSIGMLML SATQVYTILT VQLFAFLNLL PVEADILAYN FENASQTFDD LPARFGYRLP 60
AEGLKGFLIN SKPENACEPI VPPPVKDNSS GTFIVLIRRL DCNFDIKVLN AQRAGYKAAI 120
VHNVDSDDLI SMGSNDIEVL KKIDIPSVFI GESSANSLKD EFTYEKGGHL ILVPEFSLPL 180
EYYLIPFLII VGICLILIVI FMITKFVQDR HRARRNRLRK DQLKKLPVHK FKKGDEYDVC 240
AICLDEYEDG DKLRILPCSH AYHCKCVDPW LTKTKKTCPV CKQKVVPSQG DSDSDTDSSQ 300
EENEVTEHTP LLRPLASVSA QSFGALSESR SHQNMTESSD YEEDDNEDTD SSDAENEINE 360
HDVVVQLQPN GERDYNIANT V 382
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0967--Endosome
KW-0325--Glycoprotein
KW-0333--Golgi apparatus
KW-0436--Ligase
KW-0458--Lysosome
KW-0472--Membrane
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0832--Ubl conjugation
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003137--PA_domain
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF02225--PA
PF13639--zf-RING_2

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0031902--C:late endosome membrane
GO:0005765--C:lysosomal membrane
GO:0005637--C:nuclear inner membrane
GO:0016874--F:ligase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0051865--P:protein autoubiquitination