dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0001574
Uniprot Accession O43556; SGCE_HUMAN; B2R8N2; D6W5Q8; E9PF60; G5E9K6; Q6L8P0; Q75MH8; Q8NFG8; Q8WW28;
Genbank Protein ID NP_001092870.1; NP_001092871.1; NP_001288068.1; NP_003910.1;
Genbank Nucleotide ID NM_001099400.1; NM_001099401.1; NM_001301139.1; NM_003919.2;
Protein Name Epsilon-sarcoglycan
Protein Synonyms/Alias
Gene Name SGCE
Gene Synonyms/Alias ESG;UNQ433/PRO840;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Phosphorylation Sites
 dbPAF PTMs: 10
PositionPeptidesSourceReferences ( PMIDs )
32MSPATTGTFLLTVYSPhosphoSitePlus22135298
36TTGTFLLTVYSIFSKPhosphoSitePlus22135298
38GTFLLTVYSIFSKVHPhosphoSitePlus22135298
39TFLLTVYSIFSKVHSPhosphoSitePlus22135298
46SIFSKVHSDRNVYPSPhosphoSitePlus22135298
249PQNQLRCSQEMEPVIPhosphoSitePlus22135298
257QEMEPVITCDKKFRTPhosphoSitePlus22135298
337VLFLILAYIMCCRREPhosphoSitePlus22135298
353VEKRNMQTPDIQLVHPhosphoSitePlus;curated22135298; 25627689; 24961811
406PPLHTDNYDSTNMPLPhosphoSitePlus22135298
Sequence
(Fasta)		MQLPRWWELG DPCAWTGQGR GTRRMSPATT GTFLLTVYSI FSKVHSDRNV YPSAGVLFVH 60
VLEREYFKGE FPPYPKPGEI SNDPITFNTN LMGYPDRPGW LRYIQRTPYS DGVLYGSPTA 120
ENVGKPTIIE ITAYNRRTFE TARHNLIINI MSAEDFPLPY QAEFFIKNMN VEEMLASEVL 180
GDFLGAVKNV WQPERLNAIN ITSALDRGGR VPLPINDLKE GVYVMVGADV PFSSCLREVE 240
NPQNQLRCSQ EMEPVITCDK KFRTQFYIDW CKISLVDKTK QVSTYQEVIR GEGILPDGGE 300
YKPPSDSLKS RDYYTDFLIT LAVPSAVALV LFLILAYIMC CRREGVEKRN MQTPDIQLVH 360
HSAIQKSTKE LRDMSKNREI AWPLSTLPVF HPVTGEIIPP LHTDNYDSTN MPLMQTQQNL 420
PHQTQIPQQQ TTGKWYP 438
Keyword

KW-0025--Alternative splicing
KW-1003--Cell membrane
KW-0966--Cell projection
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0225--Disease mutation
KW-1023--Dystonia
KW-0325--Glycoprotein
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0832--Ubl conjugation
Interpro

IPR006644--Cadg
IPR008908--Sarcoglycan_alpha/epsilon
IPR030775--SGCE
PROSITE
Pfam

PF05510--Sarcoglycan_2
Gene Ontology

GO:0005856--C:cytoskeleton
GO:0030425--C:dendrite
GO:0032590--C:dendrite membrane
GO:0016010--C:dystrophin-associated glycoprotein complex
GO:0005794--C:Golgi apparatus
GO:0005887--C:integral component of plasma membrane
GO:0005886--C:plasma membrane
GO:0016012--C:sarcoglycan complex
GO:0042383--C:sarcolemma
GO:0007160--P:cell-matrix adhesion
GO:0007517--P:muscle organ development