dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0001573
Uniprot Accession O43555; GON2_HUMAN; Q14C68; Q14C69; Q9BYN9; Q9BYP0;
Genbank Protein ID NP_001297149.1; NP_001492.1; NP_847901.1; NP_847902.1;
Genbank Nucleotide ID NM_001310220.1; NM_001501.1; NM_178331.1; NM_178332.1;
Protein Name Progonadoliberin-2
Protein Synonyms/Alias Progonadoliberin II;
Gene Name GNRH2
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones.
Phosphorylation Sites
 dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
15LLLLLLLTAHLGPSEPhosphoSitePlus22135298
Sequence
(Fasta)		MASSRRGLLL LLLLTAHLGP SEAQHWSHGW YPGGKRALSS AQDPQNALRP PGRALDTAAG 60
SPVQTAHGLP SDALAPLDDS MPWEGRTTAQ WSLHRKRHLA RTLLTAAREP RPAPPSSNKV 120
121
Keyword

KW-0025--Alternative splicing
KW-0027--Amidation
KW-0165--Cleavage on pair of basic residues
KW-0181--Complete proteome
KW-0372--Hormone
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0964--Secreted
KW-0732--Signal
Interpro

IPR002012--GnRH
IPR019792--Gonadoliberin_I
PROSITE

PS00473--GNRH
Pfam

PF00446--GnRH
Gene Ontology

GO:0005576--C:extracellular region
GO:0005615--C:extracellular space
GO:0005183--F:gonadotropin hormone-releasing hormone activity
GO:0031530--F:gonadotropin-releasing hormone receptor binding
GO:0005179--F:hormone activity
GO:0007275--P:multicellular organismal development
GO:0046883--P:regulation of hormone secretion
GO:0000003--P:reproduction
GO:0007165--P:signal transduction