dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0001552
Uniprot Accession O43491; E41L2_HUMAN; B4DHI8; E9PPD9; Q5T4F0; Q68DV2;
Genbank Protein ID NP_001129026.1; NP_001129027.1; NP_001239589.1; NP_001422.1; XP_011533832.1; XP_011533836.1;
Genbank Nucleotide ID NM_001135554.1; NM_001135555.3; NM_001252660.1; NM_001431.3; XM_011535530.1; XM_011535534.1;
Protein Name Band 4.1-like protein 2
Protein Synonyms/Alias Generally expressed protein 4.1;4.1G;
Gene Name EPB41L2
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 77 (View all)
PositionPeptidesSourceReferences ( PMIDs )
2------MTTEVGSVScurated25850435; 25627689
3-----MTTEVGSVSEcurated25850435; 25627689
7-MTTEVGSVSEVKKDPhosphoSitePlus;curated22135298; 25850435; 25627689
9TTEVGSVSEVKKDSScurated25627689
15VSEVKKDSSQLGTDAPhosphoSitePlus;curated22135298; 22798277
16SEVKKDSSQLGTDATPhosphoSitePlus;curated22135298; 22199227
20KDSSQLGTDATKEKPPhosphoSitePlus22135298
23SQLGTDATKEKPKEVPhosphoSitePlus22135298
38AENQQNQSSDPEEEKdbPTM 3.0;HPRD 9;PhosphoSitePlus;curated20886841; 16381945; 23193290; 19651622; 18988627; 22135298;
39ENQQNQSSDPEEEKGdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;UniProt;curated15302935; 19413330; 16381945; 23193290; 18510355; 20886841;
47DPEEEKGSQPPPAAEdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoPep 2.0;PhosphoSitePlus;curated17525332; 16381945; 23193290; 18077418; 18988627; 19060867;
55QPPPAAESQSSLRRQdbPTM 3.0;Phospho.ELM 9.0;PhosphoPep 2.0;PhosphoSitePlus;curated18220336; 16381945; 23193290; 19276368; 19060867; 22135298;
57PPAAESQSSLRRQKRdbPTM 3.0;Phospho.ELM 9.0;PhosphoPep 2.0;PhosphoSitePlus;curated18220336; 16381945; 23193290; 21659604; 19060867; 22135298;
58PAAESQSSLRRQKREdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;UniProt;curated17287340; 18220336; 19413330; 16381945; 23193290; 18578522;
87PWLKKQKSYTLVVAKdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PHOSIDA;PhosphoSitePlus;SysPTM 2.0;UniProt;curated17287340; 16381945; 23193290; 18578522; 19276368; 20068231;
88WLKKQKSYTLVVAKDdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoSitePlus;SysPTM 2.0;curated19413330; 16381945; 23193290; 18669648; 18083107; 18180459;
89LKKQKSYTLVVAKDGdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PHOSIDA;PhosphoSitePlus;SysPTM 2.0;UniProt;curated16964243; 16381945; 23193290; 20068231; 20363803; 21406692;
157VSKEEKPSVSKVEMQPhosphoSitePlus22135298
159KEEKPSVSKVEMQPTPhosphoSitePlus22135298
170MQPTELVSKEREEKVPhosphoSitePlus;curated22135298; 25850435; 25627689
Sequence
(Fasta)		MTTEVGSVSE VKKDSSQLGT DATKEKPKEV AENQQNQSSD PEEEKGSQPP PAAESQSSLR 60
RQKREKETSE SRGISRFIPP WLKKQKSYTL VVAKDGGDKK EPTQAVVEEQ VLDKEEPLPE 120
EQRQAKGDAE EMAQKKQEIK VEVKEEKPSV SKEEKPSVSK VEMQPTELVS KEREEKVKET 180
QEDKLEGGAA KRETKEVQTN ELKAEKASQK VTKKTKTVQC KVTLLDGTEY SCDLEKHAKG 240
QVLFDKVCEH LNLLEKDYFG LLFQESPEQK NWLDPAKEIK RQLRNLPWLF TFNVKFYPPD 300
PSQLTEDITR YFLCLQLRQD IASGRLPCSF VTHALLGSYT LQAELGDYDP EEHGSIDLSE 360
FQFAPTQTKE LEEKVAELHK THRGLSPAQA DSQFLENAKR LSMYGVDLHH AKDSEGVDIK 420
LGVCANGLLI YKDRLRINRF AWPKILKISY KRSNFYIKVR PAELEQFEST IGFKLPNHRA 480
AKRLWKVCVE HHTFYRLVSP EQPPKAKFLT LGSKFRYSGR TQAQTRQAST LIDRPAPHFE 540
RTSSKRVSRS LDGAPIGVMD QSLMKDFPGA AGEISAYGPG LVSIAVVQDG DGRREVRSPT 600
KAPHLQLIEG KKNSLRVEGD NIYVRHSNLM LEELDKAQED ILKHQASISE LKRNFMESTP 660
EPRPNEWEKR RITPLSLQTQ GSSHETLNIV EEKKRAEVGK DERVITEEMN GKEISPGSGP 720
GEIRKVEPVT QKDSTSLSSE SSSSSSESEE EDVGEYRPHH RVTEGTIREE QEYEEEVEEE 780
PRPAAKVVER EEAVPEASPV TQAGASVITV ETVIQENVGA QKIPGEKSVH EGALKQDMGE 840
EAEEEPQKVN GEVSHVDIDV LPQIICCSEP PVVKTEMVTI SDASQRTEIS TKEVPIVQTE 900
TKTITYESPQ IDGGAGGDSG TLLTAQTITS ESVSTTTTTH ITKTVKGGIS ETRIEKRIVI 960
TGDGDIDHDQ ALAQAIREAR EQHPDMSVTR VVVHKETELA EEGED 1006
Keyword

KW-0007--Acetylation
KW-0009--Actin-binding
KW-0025--Alternative splicing
KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0903--Direct protein sequencing
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
Interpro

IPR008379--Band_4
1_C--
IPR019749--Band_41_domain
IPR000798--Ez/rad/moesin-like
IPR014847--FERM-adjacent
IPR014352--FERM/acyl-CoA-bd_prot_3-hlx
IPR019748--FERM_central
IPR019747--FERM_CS
IPR000299--FERM_domain
IPR018979--FERM_N
IPR018980--FERM_PH-like_C
IPR011993--PH/PTB_dom
IPR007477--SAB_dom
IPR029071--Ubiquitin-rel_dom
PROSITE

PS00660--FERM_1
PS00661--FERM_2
PS50057--FERM_3
Pfam

PF05902--4_1_CTD
PF08736--FA
PF09380--FERM_C
PF00373--FERM_M
PF09379--FERM_N
PF04382--SAB
Gene Ontology

GO:0030054--C:cell junction
GO:0070062--C:extracellular exosome
GO:0019898--C:extrinsic component of membrane
GO:0005925--C:focal adhesion
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0008091--C:spectrin
GO:0005198--F:structural molecule activity
GO:0030866--P:cortical actin cytoskeleton organization